Results 21 to 30 of about 12,264 (248)

The isoprenoid alcohol pathway, a synthetic route for isoprenoid biosynthesis [PDF]

open access: yesProceedings of the National Academy of Sciences, 2019
Significance We have demonstrated the design, prototyping, and implementation of a non-natural route to isoprenoid biosynthesis, termed the isoprenoid alcohol (IPA) pathway. Opposed to working within the confines of native metabolic pathways, our approach of utilizing all available biochemical reactions identified a synthetic route to ...
James M, Clomburg   +4 more
openaire   +2 more sources

Phytochemical Profiling and Untargeted Metabolite Fingerprinting of the MEDWHEALTH Wheat, Barley and Lentil Wholemeal Flours

open access: yesFoods, 2022
An important research target is improving the health benefits of traditional Mediterranean, durum wheat-based foods using innovative raw materials. In this study, we characterised wholemeal flours obtained from a traditional durum wheat cv.
Giuseppe Romano   +9 more
doaj   +1 more source

Coenzyme Q10 Biosynthesis Established in the Non-Ubiquinone Containing Corynebacterium glutamicum by Metabolic Engineering

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Coenzyme Q10 (CoQ10) serves as an electron carrier in aerobic respiration and has become an interesting target for biotechnological production due to its antioxidative effect and benefits in supplementation to patients with various diseases.
Arthur Burgardt   +8 more
doaj   +1 more source

Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2018
In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. This mutant couldn’t grow in the absence of MVA.
Sebastian Reichert   +11 more
doaj   +1 more source

A hypothesis on the capacity of plant odorant-binding proteins to bind volatile isoprenoids based on in silico evidences

open access: yeseLife, 2021
Volatile organic compounds (VOCs) from ‘emitting’ plants inform the ‘receiving’ (listening) plants of impending stresses or simply of their presence. However, the receptors that allow receivers to detect the volatile cue are elusive. Most likely, plants (
Deborah Giordano   +3 more
doaj   +1 more source

The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins

open access: yesFrontiers in Pharmacology, 2019
The mevalonate pathway provides sterols for membrane structure and nonsterol intermediates for the post-translational modification and membrane anchorage of growth-related proteins, including the Ras, Rac, and Rho GTPase family.
Huanbiao Mo   +5 more
doaj   +1 more source

Lipidomics and Comparative Metabolite Excretion Analysis of Methanogenic Archaea Reveal Organism-Specific Adaptations to Varying Temperatures and Substrate Concentrations

open access: yesmSystems, 2023
Methanogenic archaea possess diverse metabolic characteristics and are an ecologically and biotechnologically important group of anaerobic microorganisms.
Ruth-Sophie Taubner   +12 more
doaj   +1 more source

Highly branched isoprenoids and sterols in sediment core PS69/274-1 from western Amundsen Sea, Antarctica

open access: yes, 2019
Highly branched isoprenoids and sterols in sediment core PS69/274-1 from western Amundsen Sea ...
Juliane Müller (6979343)   +11 more
core   +1 more source

Mutant-Based Model of Two Independent Pathways for Carotenoid-Mediated Chloroplast Biogenesis in Arabidopsis Embryos

open access: yesFrontiers in Plant Science, 2019
Chloroplasts are essential for autonomous plant growth, and their biogenesis is a complex process requiring both plastid and nuclear genome. One of the essential factors required for chloroplast biogenesis are carotenoids.
Eva Vranová   +3 more
doaj   +1 more source

Current Metabolic Engineering Strategies for Photosynthetic Bioproduction in Cyanobacteria

open access: yesMicroorganisms, 2023
Cyanobacteria are photosynthetic microorganisms capable of using solar energy to convert CO2 and H2O into O2 and energy-rich organic compounds, thus enabling sustainable production of a wide range of bio-products.
Alessandro Satta   +2 more
doaj   +1 more source

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