Results 61 to 70 of about 20,875 (302)

Sintesis de isoxazoles utilizando ultrasonido, para su posterior oxidacion y medicion de actividad biologica [PDF]

open access: yes, 2008
63 p.Los isoxazoles presentan una gran cantidad de actividades biológicas entre las que se puede destacar actividad antifungica y antiagregante plaquetaria, entre otras, pero existen registros que las diferentes actividades biológicas de estos compuestos
Barrios Fuentes, Pedro   +1 more
core  

Cyclodextrin-based catalysts and molecular reactors [PDF]

open access: yes, 2015
We suggest two nonparametric approaches, based on kernel methods and orthogonal series to estimating regression functions in the presence of instrumental variables. For the first time in this class of problems, we derive optimal convergence rates, and
Easton, Christopher J.
core   +1 more source

An Intramolecular Wittig Approach toward Heteroarenes: Synthesis of Pyrazoles, Isoxazoles, and Chromenone-oximes.

open access: yesOrganic Letters, 2019
α-Halohydrazones/ketoximes are transformed into trisubstituted pyrazoles/disubstituted isoxazoles by treatment with phosphine, acyl chloride, and a base.
Pankaj V Khairnar   +7 more
semanticscholar   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Síntesis y evaluación “in vitro” de la actividad antifúngica de oximas, éteres de oxima e isoxazoles

open access: yesUniversitas Scientiarum, 2011
Synthesis and in vitro assessment of antifungal activity of oximes, oxime ethers and isoxazoles. Objective. To synthesize and carryout a preliminary evaluation of the in vitro antifungal activity of oximes, oxime ethers and isoxazoles.
John Diaz-Velandia   +3 more
doaj  

WONOEP XVII appraisal: The immunopathogenesis of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak   +12 more
wiley   +1 more source

Synthesis and biological evaluation of 4-phenoxy-phenyl isoxazoles as novel acetyl-CoA carboxylase inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Acetyl-CoA carboxylase (ACC) is a crucial enzyme in fatty acid metabolism, which plays a major role in the occurrence and development of certain tumours.
Xin Wu, Yongbo Yu, Tonghui Huang
doaj   +1 more source

Iterative approach to computational enzyme design [PDF]

open access: yes, 2012
A general approach for the computational design of enzymes to catalyze arbitrary reactions is a goal at the forefront of the field of protein design. Recently, computationally designed enzymes have been produced for three chemical reactions through the ...
Blomberg, Rebecca   +8 more
core   +2 more sources

Catalyst Control in Positional-Selective C-H Alkenylation of Isoxazoles and a Ruthenium-Mediated Assembly of Trisubstituted Pyrroles.

open access: yesOrganic Letters, 2019
High levels of catalyst control are demonstrated in determining the positional selectivity in C-H alkenylation of isoxazoles. A cationic rhodium-mediated, strong-directing group promotes C( sp2)-H activation at the proximal aryl ring whereas, the ...
Pravin Kumar, M. Kapur
semanticscholar   +1 more source

NMR‐Based Structural Analysis of Highly Substituted Pyridines From Kondrat'eva Aza‐Diels–Alder Cycloadditions

open access: yesMagnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno   +6 more
wiley   +1 more source

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