Results 51 to 60 of about 5,382 (243)

Inverse electron-demand 1,3-dipolar cycloaddition of nitrile oxide with common nitriles leading to 3-functionalized 1,2,4-oxadiazoles [PDF]

, 2011
A carbamoyl-substituted nitrile oxide was generated upon treatment of easily available 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with THF (not dried); the reaction proceeded efficiently even in the absence of any special reagents and reaction conditions ...
1020, 1021, 1022, 1023, 1024, 1025, 1026, 1027, Ariga, Masahiro, Hirao, Shotaro, Ise, Yumiko, Kobiro, Kazuya, Nishiwaki, Nagatoshi, Okajima, Yoshikazu, Saigo, Kazuhiko, Sawayama, Jun   +15 more
core   +1 more source

Efficacy of oral sarolaner for the treatment of generalized demodicosis in dogs

Brazilian Journal of Veterinary Medicine, 2019
The aim of this study was to report the treatment efficacy of generalized demodicosis with oral sarolaner in dogs. Twenty-seven dogs diagnosed with generalized demodicosis were treated with oral sarolanerat a dose of 2.0 mg/kg every 30 days.
Flavia Clare Goulart Carvalho, Natália Lôres Lopes, Marília Alves Machado, Alexandre Merlo, Julio Israel Fernandes   +4 more
doaj   +1 more source

Estimated seroprevalence of Ehrlichia canis in dogs in a remote community in the Northern Territory, Australia

Australian Veterinary Journal, EarlyView.
Background The emergence of Ehrlichia canis in northern Australia in 2020 has reshaped the landscape of tick‐borne diseases in dogs, particularly in rural and remote communities where the brown dog tick (Rhipicephalus linnaei) is endemic. Despite the rapid spread of ehrlichiosis and reported impacts on dog health, its prevalence remains poorly ...
E Shepherdson, K Doust, JH Hoopes, AD Barbosa, J McNeill   +4 more
wiley   +1 more source

Oxime radicals: generation, properties and application in organic synthesis

Beilstein Journal of Organic Chemistry, 2020
N-Oxyl radicals (compounds with an N–O• fragment) represent one of the richest families of stable and persistent organic radicals with applications ranging from catalysis of selective oxidation processes and mechanistic studies to production of polymers,
Igor B. Krylov, Stanislav A. Paveliev, Alexander S. Budnikov, Alexander O. Terent’ev   +3 more
doaj   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, EarlyView.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclopenta[d]isoxazolines [PDF]

, 2016
The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclo-penta[d ]isoxazolines led with good yields to corresponding fluorinated β -hydroxyketones.
Antonevich, I. P., Katok, Ya. M., Nesterova, S. V.   +2 more
core  

Randomised, Double‐Blinded, Placebo‐Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions

Veterinary Dermatology, EarlyView.
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Evi I. Sofou, Elisa Samuel, Svetlina Aleksandrova, Manolis Chatzis, Manolis N. Saridomichelakis   +4 more
wiley   +1 more source

Efficacy of fluralaner against canine generalized demodicosis

Brazilian Journal of Veterinary Medicine, 2019
Demodicosis is a parasitic dermatopathy, resulting from the excessive proliferation of Demodex mites. The rate at which this disease is encountered in the pet clinic is high, despite recent advances in the treatment of the disease. The aim of this study,
Natália Lôres Lopes, Flavia Clare Goulart Carvalho, Renata Berman, Marília Alves Machado, Carolina de Moraes Barbalho Trivisol-Medeiros, Julio Israel Fernandes   +5 more
doaj   +1 more source

Systemic insecticide treatment of the canine reservoir of Trypanosoma cruzi induces high levels of lethality in Triatoma infestans, a principal vector of Chagas disease [PDF]

, 2017
BACKGROUND: Despite large-scale reductions in Chagas disease prevalence across Central and South America, Trypanosoma cruzi infection remains a considerable public health problem in the Gran Chaco region
Bern, Caryn, Cahuasiri, Thalia, Canaviri, Ruben J., Courtenay, Orin, Gomez, Sonia A., Goncalves, Raquel, Guibarra, Alvaro, Herbas, Gladys, Loza, Ariel, Luck, Laura, Messenger, Louisa A., Pereira, Juan A., Picado de Puig, Albert, Talaga, Adrianna   +13 more
core   +3 more sources