Results 81 to 90 of about 1,462 (171)

Should SVGp12 Be Used for JC Polyomavirus Studies? Comment on Prezioso et al. COS-7 and SVGp12 Cellular Models to Study JCPyV Replication and MicroRNA Expression after Infection with Archetypal and Rearranged-NCCR Viral Strains. Viruses 2022, 14, 2070 [PDF]

, 2022
A recent paper in Viruses investigates the impact of the JC polyomavirus (JCPyV) microRNA on the replication of different JCPyV strains. Unfortunately, one of the cell lines used, the human fetal glial cell line SVGp12, is productively infected by the ...
Stian Henriksen, Christine Hanssen Rinaldo, Rinaldo, Christine Hanssen, Henriksen, Stian   +3 more
core   +1 more source

Multiple DNA Viruses and HPV Integration in Inverted Papilloma and Associated Sinonasal Carcinoma

The Laryngoscope, Volume 135, Issue 2, Page 677-686, February 2025.
HPV6 integration was observed in benign inverted papilloma, whereas HPV16 is present pre‐ and post‐malignant transformation. Marked increase in viral diversity was present, supported by accumulation of mutations over time. Objectives Sinonasal inverted papilloma (IP) has a locally destructive growth pattern, can relapse, and can undergo malignant ...
Maria K. Jauhiainen, Lari Pyöriä, Sanna Viitasalo, Ushanandini Mohanraj, Leena‐Maija Aaltonen, Maria Söderlund‐Venermo, Jaana Hagström, Antti A. Mäkitie, Maria F. Perdomo, Saku T. Sinkkonen   +9 more
wiley   +1 more source

Extracellular vesicles promote the infection and pathogenicity of Japanese encephalitis virus

Journal of Extracellular Vesicles, Volume 14, Issue 1, January 2025.
Abstract Japanese encephalitis virus (JEV) is a neurotropic zoonotic pathogen that poses a serious threat to public health. Currently, there is no specific therapeutic agent available for JEV infection, primarily due to the complexity of its infection mechanism and pathogenesis.
Junyao Xiong, Ling'en Yang, Xiaowei Nan, Shuo Zhu, Mengxue Yan, Shengxian Xiang, Luping Zhang, Qi Li, Chengjie Yang, Xugang Wang, Ning Wei, Huanchun Chen, Youhui Si, Shengbo Cao, Jing Ye   +14 more
wiley   +1 more source

High-Throughput Characterization of Viral and Cellular Protein Expression Patterns During JC Polyomavirus Infection

Frontiers in Microbiology, 2019
JC polyomavirus (JCPyV) is a ubiquitous human pathogen and the causative agent of a fatal demyelinating disease in severely immunocompromised individuals.
Jeanne K. DuShane, Michael P. Wilczek, Mason A. Crocker, Melissa S. Maginnis, Melissa S. Maginnis   +4 more
doaj   +1 more source

Cellular Immunity Against BK Polyomavirus in Kidney Transplant Recipients: A Comprehensive Review

Transplant Infectious Disease, Volume 27, Issue 1, January/February 2025.
ABSTRACT BK polyomavirus (BKPyV) is an important opportunistic viral infection that complicates kidney transplantation. Uncontrolled viral replication may result in BKPyV‐associated nephropathy (BKPyVAN), a major cause of premature allograft damage and failure.
Mohammed Al‐Talib, Anna Skaria, Siân Griffin   +2 more
wiley   +1 more source

Increased prevalence of Human Polyomavirus JC viruria in Chronic Inflammatory Rheumatic Diseases patients in treatment with anti-TNF α: a 18 month follow-up study.

Frontiers in Microbiology, 2016
Chronic inflammatory rheumatic diseases (CIRDs) are immune-mediated pathologies involving joints. To date, TNFα-blocking agents administration is the most promising therapy, although these treatments are associated with an increased Polyomavirus JC ...
Donatella Maria Rodio, Elena eAnzivino, Monica eMischitelli, Anna eBellizzi, Rossana eScrivo, Daniela eScribano, Gianlorenzo eConte, Carla ePrezioso, Maria eTrancassini, Guido eValesini, Anna Teresa ePalamara, Valeria ePietropaolo   +11 more
doaj   +1 more source

Exploring the Causal Relationship Between Mitochondrial DNA Copy Number, Antibody‐Mediated Immune Response, and Risk of Kidney Stone Disease: A Mendelian Randomization Study

International Journal of Clinical Practice, Volume 2025, Issue 1, 2025.
Background Given the high recurrence rate of kidney stone disease (KSD), surgical interventions alone are not an optimal solution. Antibody‐mediated immune responses and mitochondrial dysfunction influence the risk and prognosis of KSD; however, the exact causal mechanisms underlying these relationships remain unclear.
Wenqiong Chen, Yan Qian, Zhongqiu Xie
wiley   +1 more source

Mouse polyomavirus infection induces lamin reorganisation

The FEBS Journal, Volume 291, Issue 23, Page 5133-5155, December 2024.
Here, we investigated the roles of lamins as important nuclear proteins in the replication cycle of the mouse polyomavirus. We detected accumulation of the major capsid protein VP1 under the nuclear lamina, defects in nuclear lamina staining and different lamin A/C phosphorylation patterns following viral infection.
Kateřina Bruštíková, Boris Ryabchenko, Sandra Žáčková, Vojtěch Šroller, Jitka Forstová, Lenka Horníková   +5 more
wiley   +1 more source

Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus

Cell Reports, 2019
Summary: JC polyomavirus (JCPyV) is a ubiquitous human pathogen that causes progressive multifocal leukoencephalopathy (PML). The entry receptors for JCPyV belong to the 5-hydroxytryptamine 2 receptor (5-HT2R) family, but how individual members of the ...
Benedetta Assetta, Jenna Morris-Love, Gretchen V. Gee, Abigail L. Atkinson, Bethany A. O’Hara, Melissa S. Maginnis, Sheila A. Haley, Walter J. Atwood   +7 more
doaj   +1 more source

BK Polyomavirus Infection of Bladder Microvascular Endothelial Cells Leads to the Activation of the cGAS‐STING Pathway

Journal of Medical Virology, Volume 96, Issue 11, November 2024.
ABSTRACT BK polyomavirus (BKPyV) infection in humans is usually asymptomatic but ultimately results in viral persistence. In immunocompromised hosts, virus reactivation can lead to nephropathy or hemorrhagic cystitis. The urinary tract serves as a silent reservoir for the virus.
Kateřina Bruštíková, Boris Ryabchenko, David Liebl, Lenka Horníková, Jitka Forstová, Sandra Huérfano   +5 more
wiley   +1 more source