Results 71 to 80 of about 1,462 (171)
, 2022 Natalizumab (NTZ) can reactivate human polyomavirus John Cunningham polyomavirus (JCPyV) latent infection and lead to progressive multifocal leukoencephalopathy (PML). NTZ modulates the expression of microRNA-126-3p (miR-126-3p) and its target genes, Spi-
Daniela Galimberti (253047) +6 more
core +1 more source
Detection analysis and study of genomic region variability of JCPyV, BKPyV, MCPyV, HPyV6, HPyV7 and QPyV in the urine and plasma of HIV-1-infected patients [PDF]
, 2022 Since it was clearly established that HIV/AIDS predisposes to the infection, persistence or reactivation of latent viruses, the prevalence of human polyomaviruses (HPyVs) among HIV-1-infected patients and a possible correlation between HPyVs and HIV ...
Carla Prezioso +23 more
core +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. The John Cunningham virus (JCPyV) causes a fatal demyelinating disease of the central nervous system known as progressive multifocal leukoencephalopathy (PML). In healthy people, the JCPyV non-coding control region (NCCR) is not rearranged,
Marina A. Tyumentseva +6 more
doaj +1 more source
Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines
MicrobiologyOpen, Volume 14, Issue 5, October 2025.In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Setsuko Shioda +6 more
wiley +1 more source
Advanced Science, Volume 12, Issue 35, September 18, 2025.Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification.
Linlin Cheng +6 more
wiley +1 more source
Analyzing JCPyV caused changes of microRNA expression in PML patients
, 2023 Progressive Multifocal Leukoencephalopathy (PML) is a rare but often fatal central nervous system demyelination disease caused by the reactivation of persistent JC polyomavirus (JCPyV) in immunosuppressed individuals.
Suppula, Joni Johan Mikael
core
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
European Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina +8 more
wiley +1 more source
Generation of JC Polyoma Pseudovirus for High-Throughput Measurement of Neutralizing Antibodies
DiagnosticsProgressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by reactivation of dormant JC polyomavirus (JCPyV).
Mami Matsuda +10 more
doaj +1 more source
mBio, 2023 JC polyomavirus (JCPyV) is a ubiquitous, double-stranded DNA virus that causes the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML) in immunocompromised patients. Current treatments for PML are limited to immune reconstitution,
Jacob Kaiserman +5 more
doaj +1 more source
The potential of long‐term wastewater‐based surveillance to predict COVID‐19 waves peak in Mexico
Water Environment Research, Volume 97, Issue 5, May 2025.Wastewater‐based surveillance (WBS) predicted COVID‐19 wave onsets with varying lead times influenced by SARS‐CoV‐2 variants. Delta and Omicron waves showed lead times of 5–14 and 1–4 days, respectively. WBS aligned with case reports but overestimated peaks due to variant transmissibility, highlighting its potential and limitations in public health ...
Marcela Zavala‐Méndez +5 more
wiley +1 more source