Results 191 to 200 of about 47,334 (259)
Activation of kainate receptor GluK2-Neto2 complex. [PDF]
Nat Struct Mol BiolGangwar SP +4 more
europepmc +1 more source
Potential of Khaya senegalensis to mitigate epileptogenesis and cognitive dysfunction on kainate-induced post-status epilepticus model. [PDF]
IBRO Neurosci RepKandeda AK, Foutse LY, Lewale S, Dimo T.
europepmc +1 more source
Causal association between sepsis and acute respiratory distress syndrome: Evidence from a 2-sample Mendelian randomization study. [PDF]
Medicine (Baltimore)Zhang P +8 more
europepmc +1 more source
Magnetic Resonance Imaging of Progressive Changes in Traumatic Brain Injury and Epileptogenesis (Aivomuutosten magneettikuvantaminen traumaattisen päävamman ja epilepsian kehitysvaiheiden aikana) [PDF]
Immonen, Riikka
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Kainate receptors in the hippocampus
European Journal of Neuroscience, 2014AbstractKainate receptors (KARs) consist of a family of ionotropic glutamate receptors composed of the combinations of five subunits, GluK1–GluK5. Although KARs display close structural homology with AMPA receptors, they serve quite distinct functions.
M. Carta +3 more
semanticscholar +3 more sources
Physiopathology of kainate receptors in epilepsy.
Current Opinion in Pharmacology, 2015Kainate receptors (KARs) are tetrameric ionotropic glutamate receptors composed of the combinations of five subunits GluK1-GluK5. KARs are structurally related to AMPA receptors but they serve quite distinct functions by regulating the activity of synaptic circuits at presynaptic and postsynaptic sites, through either ionotropic or metabotropic actions.
Valérie Crépel, C. Mulle
semanticscholar +3 more sources
The Neuroscientist, 2014
Ionotropic glutamate receptors of the N-methyl-d-aspartate (NMDA)- and AMPA-type, as well as metabotropic glutamate receptors have been extensively invoked in plasticity. Until relatively recently, however, kainate-type receptors (KARs) had been the most elusive to study because of the lack of appropriate pharmacological tools to specifically address ...
T. Sihra +2 more
semanticscholar +3 more sources
Ionotropic glutamate receptors of the N-methyl-d-aspartate (NMDA)- and AMPA-type, as well as metabotropic glutamate receptors have been extensively invoked in plasticity. Until relatively recently, however, kainate-type receptors (KARs) had been the most elusive to study because of the lack of appropriate pharmacological tools to specifically address ...
T. Sihra +2 more
semanticscholar +3 more sources
Desensitization of Kainate Receptors by Kainate, Glutamate and Diastereomers of 4-Methylglutamate
Neuropharmacology, 1997The potencies of kainate, glutamate and diastereomers of 4-methylglutamate were determined for activation and steady-state desensitization of GluR6 and dorsal root ganglion-type kainate receptors using whole-cell voltage clamp. In HEK293 cells expressing GluR6, all four diastereomers induced desensitizing inward currents at relatively high ...
James E Huettner
exaly +3 more sources
Journal of Chemical Neuroanatomy, 2020
Oxidative stress, inflammation and pyroptosis are three of the most important mechanisms in the pathophysiology of temporal lobe epilepsy (TLE). Most people with TLE are refractory to the existing drugs.
Samira Ramazi +7 more
semanticscholar +1 more source
Oxidative stress, inflammation and pyroptosis are three of the most important mechanisms in the pathophysiology of temporal lobe epilepsy (TLE). Most people with TLE are refractory to the existing drugs.
Samira Ramazi +7 more
semanticscholar +1 more source