Results 201 to 210 of about 47,334 (259)
Kainate receptors and synaptic plasticity
Neuropharmacology, 2021 Synaptic plasticity has classically been characterized to involve the NMDA and AMPA subtypes of glutamate receptors, with NMDA receptors providing the key trigger for the induction of long-term plasticity leading to changes in AMPA receptor expression.
Jithin D Nair +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Cell and Tissue Research, 2006
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
openaire +2 more sources
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
openaire +2 more sources
Current Opinion in Neurobiology, 2000
Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
openaire +2 more sources
Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
openaire +2 more sources
Comparative Antagonism of Kainate-activated Kainate and AMPA Receptors in Hippocampal Neurons
European Journal of Neuroscience, 1996 AbstractNative kainate receptors expressed by cultured hippocampal cells were studied in the whole‐cell configuration of the patch‐clamp technique by using a fast perfusion system. About 80% of the neurons expressed kainate receptors independently of the time in culture (0–4 days), which coincided with the number of cells immunoreactive for a ...
Angeles Vicente, Juan Lerma
exaly +4 more sources
Kainate induces various domain closures in AMPA and kainate receptors
Neurochemistry International, 2012Ionotropic glutamate receptors are key players in fast excitatory synaptic transmission within the central nervous system. These receptors have been divided into three subfamilies: the N-methyl-d-aspartic acid (NMDA), 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and kainate receptors.
Venskutonyte, Raminta +6 more
openaire +3 more sources
2010
Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
openaire +2 more sources
Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
openaire +2 more sources
Neuropharmacology of AMPA and kainate receptors
Neuropharmacology, 1998D, Bleakman, D, Lodge
exaly +3 more sources
Role of kainate receptors in nociception
Brain Research Reviews, 2002Nociceptive nerve fibers use L-glutamate as a fast excitatory neurotransmitter and it is therefore not surprising that both, ionotropic and metabotropic glutamate receptors play pivotal roles for transmission of nociceptive information in spinal cord.
Ruth, Ruscheweyh, Jürgen, Sandkühler
openaire +2 more sources
Kainate neurotoxicity and glutamate inactivation
Neuroscience Letters, 1979Dihydrokainate, an inhibitor of high affinity L-glutamate as an excitant of cat spinal neurones in vivo. This action of dihydrokainate was selective in that the effects of excitants taken up actively in vitro by CNS tissue (L-aspartate, D- and L-glutamate and L-homocysteate) were enhanced whereas those of other substances not taken up (acetylcholine, D-
D, Lodge +3 more
openaire +2 more sources
Kainate-like neurotoxicity of folates
Nature, 1981Kainic acid (KA) is one of the most powerful of a group of ‘excitotoxic’ analogues of the putative neurotransmitter glu-tamate (Glu) whose neurotoxicity may involve an excitatory mechanism mediated through glutamergic postsynaptic receptors1–8. The finding9 that neural membranes have specific sites where KA binds quite firmly and that Glu inhibits such
J W, Olney, T A, Fuller, T, de Gubareff
openaire +2 more sources