Results 21 to 30 of about 4,896 (130)
Viruses, 2021 Background: Coronavirus disease 19 (COVID-19) can develop into a severe respiratory syndrome that results in up to 40% mortality. Acute lung inflammatory edema is a major pathological finding in autopsies explaining O2 diffusion failure and hypoxemia ...
Eli Mansour +19 more
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Cardiovascular Activities of of the bradykinin system
The Scientific World Journal, 2008 All the components of the kallikrein-kinin system are located in the cardiac muscle andits deficiency may lead to cardiac dysfunction. In recent years, numerous observationsobtained from clinical and experimental models of diabetes, hypertension ...
Jagdish N. Sharma
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Бюллетень сибирской медицины, 2012 The activity of kallikrein-kinin system of blood and the state of placental circulation at full-term physiological pregnancy have been studied.In 30 pregnant women aged 18—27 at 38th—40th weeks of pregnancy, the activity of kallikrein-kinin system (KKS)
G. T. Kairov +2 more
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Pharmaceuticals, 2010 Terrestrial animals must conserve water and NaCl to survive dry environments. The kidney reabsorbs 95% of the sodium filtered from the glomeruli before sodium reaches the distal connecting tubules. Excess sodium intake requires the renal kallikrein-kinin
Masataka Majima, Makoto Katori
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Mutant plasminogen in hereditary angioedema is bypassing FXII/kallikrein to generate bradykinin
Frontiers in Physiology, 2023 Hereditary angioedema (HAE) is characterized by recurrent localized edema in various organs, which can be potentially fatal. There are different types of hereditary angioedema, which include genetic deficiency of C1 inhibitor (C1-INH) and hereditary ...
Stefan Hintze +12 more
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The Kallikrein-Kinin System: Current and Future Pharmacological Targets
Journal of Pharmacological Sciences, 2005 The kallikrein-kinin system is an endogenous metabolic cascade, triggering of which results in the release of vasoactive kinins (bradykinin-related peptides). This complex system includes the precursors of kinins known as kininogens and mainly tissue and
Marie Eve Moreau +5 more
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GastroenterologìaBackground. Clinical practice and science have accumulated data that obese patients suffer from severe forms of acute and chronic pancreatitis, which is explained by the accumulation of fat around the pancreas, a decreased activity of pancreatic enzymes.
L.S. Babinets +2 more
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Optimization of Transfusion Therapy in Peritonitis
Общая реаниматология, 2009 Objective: to develop approaches to therapy for postoperative peritonitis on the basis of an analysis of changes into some indices of the kallikrein-kinin system, such as the key plasma proteolytic system and the blood proteinase potential, in this ...
Ye. V. Ryabikina +3 more
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A Missing Link Between a High Salt Intake and Blood Pressure Increase
Journal of Pharmacological Sciences, 2006 .: It is widely accepted that a high sodium intake triggers blood pressure rise. However, only one-third of the normotensive subjects were reported to show salt-sensitivity in their blood pressure.
Makoto Katori, Masataka Majima
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The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. [PDF]
PLoS ONE, 2018 Oversulfated chondroitin sulfate (OSCS) was identified as a contaminant in certain heparin preparations as the cause of adverse reactions in patients. OSCS was found to possess both plasma anticoagulant activity and the ability to activate prekallikrein ...
J Hogwood +6 more
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