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Cardiovascular Properties of the Kallikrein-Kinin System

Current Medical Research and Opinion, 2002
All the components of the kallikrein-kinin system are located in the vascular smooth muscle as well as in the heart. In recent years, numerous observations obtained from clinical and experimental models of diabetes, hypertension, cardiac failure, ischaemia, myocardial infarction and left ventricular hypertrophy, have suggested that the reduced activity
, Jagdish N Sharma
exaly   +3 more sources

PHARMACOLOGY OF THE KALLIKREIN–KININ SYSTEM

Pharmacological Research, 1997
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REGOLI, Domenico   +2 more
openaire   +3 more sources

The Kallikrein-Kinin System

2011
Emerging evidence suggests a role of the kallikrein-kinin system (KKS) in the pathogenesis of diabetic nephropathy (DN). Tissue kallikrein 1 is a member of the tissue kallikrein family that is mainly responsible for the generation of kinins, and bradykinin (BK) is the principal kinin responsible for the biologic actions of the KKS that acts through the
Leung, JCK, Lai, KN, Tang, SCW
openaire   +4 more sources

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