Results 61 to 70 of about 4,951 (172)
Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy
Frontiers in Medicine, 2018 Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied.
Carlos C. Barros +21 more
doaj +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.ABSTRACT Chronic kidney disease (CKD) remains a significant global health burden despite recent advances in pharmacotherapy, including sodium‐glucose cotransporter 2 (SGLT2) inhibitors and mineralocorticoid receptor antagonists. Renal fibrosis, a central pathological hallmark of CKD progression, is mediated by persistent inflammation and macrophage ...
Gabriel Rufino Estrela +6 more
wiley +1 more source
Activity of kallikrein-kinin system in children in norm and at some pathological states
Бюллетень сибирской медицины, 2009 Proteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions.
Ye. I. Kondratiyeva +7 more
doaj +1 more source
Frontiers in Immunology, 2018 BackgroundThe interaction of coagulation factors has been shown to go beyond their traditional roles in hemostasis and to affect the development of inflammatory diseases.
Kerstin Göbel +5 more
doaj +1 more source
Scientific ReportsPatients with Parkinson’s disease (PD) have gastrointestinal motility disorders, which are common non-motor symptoms. However, the reasons for these motility disorders remain unclear. Increased alpha-synuclein (α-syn) is considered an important factor in
Min Hyung Seo, Soo-Hwan Kim, Sujung Yeo
doaj +1 more source
Kallikrein–Kinin System in Neovascularization [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 The formation of new blood vessels is viewed completely differently by cardiologists than by oncologists and ophthalmologists. Whereas the former try to stimulate this process, the latter put all efforts into blocking it. In any case, factors involved in neovascularization are of highest therapeutic relevance.
openaire +1 more source
Вавиловский журнал генетики и селекции, 2015 The transcriptional activity of genes was studied in kidneys of hypertensive ISIAH and normotensive WAG rats in order to detect genes significantly expressed in kidneys of just one of the analyzed strains.
O. E. Redina +5 more
doaj
Journal of Education, Health and SportBackground. Stress is one of the important causes of the development of pathological processes in the body. The salivary glands play a certain role in the pathogenesis of post-stress pathological reactions Aim.
Ya. Yuzkiv
doaj +1 more source
BMC Nephrology, 2017 Background Additional urinary biomarkers for diabetic nephropathy (DN) are needed, providing early and reliable diagnosis and new insights into its mechanisms.
Lenka Vitova +5 more
doaj +1 more source
Roles of Kinins in the Nervous System
Cell Transplantation, 2015 The kallikrein-kinin system (KKS) is an endogenous pathway involved in many biological processes. Although primarily related to blood pressure control and inflammation, its activation goes beyond these effects.
Priscilla D. Negraes +4 more
doaj +1 more source