Results 71 to 80 of about 5,220 (174)

Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation. [PDF]

Front Pharmacol, 2023
Clermont AC, Murugesan N, Edwards HJ, Lee DK, Bayliss NP, Duckworth EJ, Pethen SJ, Hampton SL, Gailani D, Feener EP.   +9 more
europepmc   +1 more source

In vitro reconstitution of kallikrein-kinin system and progress curve analysis. [PDF]

Biosci Rep, 2022
Favier B, Bicout DJ, Baroso R, Paclet MH, Drouet C.   +4 more
europepmc   +1 more source

Renin-angiotensin and kallikrein-kinin systems in diabetic retinopathy [PDF]

Scripta Medica, 2019
This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina.
Igić Rajko
doaj  

Alterations in the kallikrein-kinin system predict death after heart transplant. [PDF]

Sci Rep, 2022
Giangreco NP, Lebreton G, Restaino S, Farr M, Zorn E, Colombo PC, Patel J, Soni RK, Leprince P, Kobashigawa J, Tatonetti NP, Fine BM.   +11 more
europepmc   +1 more source

Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice

Diabetes, Metabolic Syndrome and Obesity, 2015
Rafael L Morais,1 Elton D Silva,1 Vicência M Sales,1 Rafael Filippelli-Silva,1 Marcelo A Mori,1 Michael Bader,2 João B Pesquero1 1Department of Biophysics, Universidade Federal de São Paulo, São Paulo, Brazil; 2Max-Delbrü ...
Morais RL, Silva ED, Sales VM, Filippelli-Silva R, Mori MA, Bader M, Pesquero JB   +6 more
doaj  

Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats. [PDF]

Int J Mol Sci, 2022
Youssef ME, Abdel-Reheim MA, Morsy MA, El-Daly M, Atwa GMK, Yahya G, Cavalu S, Saber S, Ahmed Gaafar AG.   +8 more
europepmc   +1 more source

Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on-demand treatment of hereditary angioedema. [PDF]

Clin Exp Allergy, 2022
Duckworth EJ, Murugesan N, Li L, Rushbrooke LJ, Lee DK, De Donatis GM, Maetzel A, Yea CM, Hampton SL, Feener EP.   +9 more
europepmc   +1 more source

Molecular mechanisms for subtype selectivity of kinin receptors’ antagonists

Nature Communications
The kinin receptors B1R and B2R act as key regulators within the kallikrein–kinin system, mediating vasodilation, inflammation, and pain. Antagonists targeting these receptors have shown therapeutic potential in the treatment of angioedema, pancreatitis,
Meng Xia, Aleksey Raskovalov, My V. T. Nguyen, Shiliu Mei, Donggyun Kim, Jayden Salve, Vsevolod Katritch, Vadim Cherezov, Haitao Zhang   +8 more
doaj   +1 more source

Targeted LC-MS/MS platform for the comprehensive determination of peptides in the kallikrein-kinin system. [PDF]

Anal Bioanal Chem, 2021
Gangnus T, Burckhardt BB.
europepmc   +1 more source

The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System. [PDF]

Front Immunol, 2021
Lipcsey M, Persson B, Eriksson O, Blom AM, Fromell K, Hultström M, Huber-Lang M, Ekdahl KN, Frithiof R, Nilsson B.   +9 more
europepmc   +1 more source