Discovery and characterization of a novel KATP channel pharmacochaperone
My work resulted in the discovery of a novel KATP channel pharmacochaperone, Aekatperone, through AI-driven virtual screening of the drug binding site using the Cryo-EM structure of the KATP channel. Additionally, I functionally characterized the effects
Elsheikh, Assmaa
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KATP channel controls LPS-induced MUC5AC overexpression in vivo
, 2020 Glybenclamide; Hypersecretion; Inflammation; KATP channel; MUC5AC ...
송경섭
core
Acute Hypoxia Inhibits K<sub>2P</sub>3/9 (TASK1/3) Independently of Cytosolic ATP in Carotid Body Type 1 Cells. [PDF]
Acta Physiol (Oxf)Kang D, Wang J, Kim D.
europepmc +1 more source
Mechanisms Underlying the Biphasic Effects of Hydrogen Sulfide in Rat Intrapulmonary Arteries. [PDF]
BiomedicinesTunaitytė A +5 more
europepmc +1 more source
Pericyte K<sub>ATP</sub> channel hyperactivity redistributes cortical blood flow in a CADASIL mouse model. [PDF]
Nat Cardiovasc ResJeffrey DA +17 more
europepmc +1 more source
Co-occurrence of Loss-of-Function GCK and ABCC8 Variants in a Pedigree With a Spectrum of Dysglycemia. [PDF]
DiabetesSaint-Martin C +6 more
europepmc +1 more source
KATP Channel Expression Determines ONC212 Sensitivity via Mitochondrial Dysfunction and PERK/ATF4/CHOP Activation in Glioblastoma. [PDF]
J Cell Mol MedTaskesen A, Hacioglu C.
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Cantú Syndrome: A Poorly Understood Multi-Organ Disorder. [PDF]
Int J Mol SciHe S, Hu D, Nichols CG, Huang Y.
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Pharmaceutical agents targeting K<sub>ATP</sub> channel modulate sweet taste sensitivity in mice. [PDF]
J Physiol SciSawai C +6 more
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Postnatal refinement of Ca<sub>V</sub> channel isoform composition, electrical activity, and insulin release in mouse pancreatic β-cells. [PDF]
Channels (Austin)Theiner T +3 more
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