Results 101 to 110 of about 1,219,583 (164)

Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion. [PDF]

BMC Res Notes, 2023
Kitamura S, Murao N, Yokota S, Shimizu M, Ono T, Seino Y, Suzuki A, Maejima Y, Shimomura K.   +8 more
europepmc   +1 more source

Effects of U-37883A, a vascular selective KATP+ channel antagonist, in the pulmonary and hindlimb circulation

, 1996
The effects of the vascular selective nonsulfonylurea guanidine ATP-sensitive K+ (KATP+) channel-blocking agent U-37883A on vasodilator and vasoconstrictor responses were investigated in the pulmonary and hindlimb vascular beds of the cat.
B. J. DeWitt, T. J. McMahon, J. R. Marrone, P. J. Kandowitz, D. Y. Cheng, H. C. Champion   +5 more
core   +1 more source

Mechanistic insights on KATP channel regulation from cryo-EM structures. [PDF]

J Gen Physiol, 2023
Driggers CM, Shyng SL.
europepmc   +1 more source

The inhibition mechanism of the SUR2A-containing K_ATP channel by a regulatory helix. [PDF]

Nat Commun, 2023
Ding D, Hou T, Wei M, Wu JX, Chen L.
europepmc   +1 more source

Closure by iptakalim, a cardiovascular KATP channel opener, of rat pancreatic β-cell KATP channels and its molecular basis [PDF]

application/pdfDiabetes mellitus is a group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both.
Wu, Jie, Wakui, Makoto, Misaki, Naoko, Suga, Sechiko, Lin, Yu-Fung, Mao, Xia   +5 more
core   +1 more source

Dose Dependent Effect of Sulfamethoxazole on Inhibiting K_ATP Channel of Mouse Pancreatic β Cell. [PDF]

Dose Response, 2023
Ogata H, Kitamura S, Fujiwara M, Shimizu M, Tan C, Zhao S, Maejima Y, Shimomura K.   +7 more
europepmc   +1 more source

Fixing a Broken Heart Opens the Door to Developing K_ATP Channel Agonists as Pain Relievers. [PDF]

J Pharmacol Exp Ther, 2023
Zambelli VO, Gross ER.
europepmc   +1 more source

CL-705G: a novel chemical Kir6.2-specific K_ATP channel opener. [PDF]

Front Pharmacol, 2023
Gando I, Becerra Flores M, Chen IS, Yang HQ, Nakamura TY, Cardozo TJ, Coetzee WA.   +6 more
europepmc   +1 more source

Protection against Ischemic Heart Disease: A Joint Role for eNOS and the K_ATP Channel. [PDF]

Int J Mol Sci, 2023
Severino P, D'Amato A, Mancone M, Palazzuoli A, Mariani MV, Prosperi S, Myftari V, Lavalle C, Forleo GB, Birtolo LI, Caputo V, Miraldi F, Chimenti C, Badagliacca R, Maestrini V, Palmirotta R, Vizza CD, Fedele F.   +17 more
europepmc   +1 more source

K_ATP channel activity and slow oscillations in pancreatic beta cells are regulated by mitochondrial ATP production. [PDF]

J Physiol, 2023
Corradi J, Thompson B, Fletcher PA, Bertram R, Sherman AS, Satin LS.   +5 more
europepmc   +1 more source