Results 81 to 90 of about 1,219,583 (164)

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Cloning and functional expression of a rat heart KATP channel

, 1994
Potassium channels that are ATP-sensitive (KATP) couple membrane potential to the metabolic status of the cell. KATP channels are inhibited by intracellular ATP and are stimulated by intracellular nucleotide diphosphates.
Ashford, M. L. J.; id_orcid, M. L. J. Ashford, C. T. Bond, J. P. Adelmair, Bond, C. T., T. A. Blair, Blair, T. A., Adelman, J. P.   +7 more
core   +1 more source

Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc

eLife, 2020
We investigated targeting mechanisms of Na+ and KATP channels to the intercalated disk (ICD) of cardiomyocytes. Patch clamp and surface biotinylation data show reciprocal downregulation of each other’s surface density.
Hua-Qian Yang, Marta Pérez-Hernández, Jose Sanchez-Alonso, Andriy Shevchuk, Julia Gorelik, Eli Rothenberg, Mario Delmar, William A Coetzee   +7 more
doaj   +1 more source

Altered neural electrophysiological properties in the anterior cingulate cortex in a mouse model of Prader‐Willi syndrome

The Journal of Physiology, Volume 604, Issue 17, Page 7313-7336, 1 September 2026.
Abstract figure legend Prader‐Willi syndrome (PWS) originates from deficiencies in chromosome 15q11‐13 region clustering around a critical region containing multiple‐repeat non‐coding RNA gene Snord116, resulting in metabolic and behavioural abnormalities leading to hyperphagia and obesity.
Volodymyr Rybalchenko, Ryan Butler
wiley   +1 more source

Alterations in ventricular KATP channel properties during aging

, 2013
Coronary heart disease remains the principle cause of mortality in the United States. During aging, the efficiency of the cardiovascular system is decreased and the aged heart is less tolerant to ischemic injury.
Ramasamy, Ravichandran, Bao, Li, Taskin, Eylem, Ananthakrishnan, Radha, Schmidt, Ann M., Rosario, Rosa, Foster, Monique, Ray, Beevash, Howlett, Susan E., Coetzee, William A.   +9 more
core   +1 more source

Regulation of mitochondrial KATP channel by redox agents [PDF]

, 1999
The ATP-dependent K+ channel (KATP) was purified from the inner mitochondrial membrane and reconstituted into lipid bilayer membranes. KATP activity was inhibited by high concentrations of ATP and ADP, but activated by low concentrations (up to 200 μM ...
Grigoriev, S.M., Skarga, Yu.Yu., Mironova, G.D., Marinov, B.S.   +3 more
core   +1 more source

KATP channel controls LPS-induced MUC5AC overexpression in vivo

, 2020
Glybenclamide; Hypersecretion; Inflammation; KATP channel; MUC5AC ...
송경섭
core   +1 more source

Inhibition of ATP-Sensitive K+ Channels and L-Type Ca2+ Channels by Amiodarone Elicits Contradictory Effect on Insulin Secretion in MIN6 Cells

Journal of Pharmacological Sciences, 2011
.: Some class I antiarrhythmic drugs induce a sporadic hypoglycemia by producing insulin secretion via inhibition of ATP-sensitive K+ (KATP) channels of pancreatic β-cells.
Atsushi Nishida, Taichi Takizawa, Akio Matsumoto, Takashi Miki, Susumu Seino, Haruaki Nakaya   +5 more
doaj   +1 more source

Iptakalim A Vascular Atp-Sensitive Potassium (Katp) Channel Opener Closes Rat Pancreatic β-Cell Katp Channels And Increases Insulin Release

, 2007
Sulfonylureas have been the leading oral antihyperglycemic agents, and they presently continue to be the most popular antidiabetic drugs prescribed for treatment of type 2 diabetes.
Lin, Yu Fung, Chang, Yongchang, Wu, Jie, Misaki, Naoko, Wakui, Makoto, Li, Guo Hui, Suga, Sechiko, Wang, Hai, Liu, Qiang, Mao, Xia   +9 more
core   +1 more source

In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat

Journal of Pharmacological Sciences, 2016
The lower esophageal sphincter (LES) is a specialized region of the esophageal smooth muscle that allows the passage of a swallowed bolus into the stomach. Nitric oxide (NO) plays a major role in LES relaxation.
Tomonori Shimbo, Takeshi Adachi, Susumu Fujisawa, Mai Hongoh, Takayoshi Ohba, Kyoichi Ono   +5 more
doaj   +1 more source