Results 41 to 50 of about 20,432 (180)
Chromosome Oscillations in Mitosis [PDF]
, 2005 Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar +8 more
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Cell Division: Kinetochores SKAdaddle [PDF]
Current Biology, 2013 Accurate chromosome segregation during cell division requires that kinetochores couple microtubule dynamics to chromosome movement. New research reveals that the kinetochore-associated Ska1 complex hangs on to depolymerizing microtubules and brings some important friends along for the ride.
Ye, Anna A., Maresca, Thomas J.
openaire +2 more sources
Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing
Cell Reports, 2019 Summary: Faithful chromosome segregation relies on the ability of the spindle assembly checkpoint (SAC) to delay anaphase onset until chromosomes are attached to the mitotic spindle via their kinetochores.
Spyridon T. Pachis +4 more
doaj +1 more source
Dynamic rearrangement of nucleoporins during fungal "open" mitosis [PDF]
, 2008 Mitosis in animals starts with the disassembly of the nuclear pore complexes and the breakdown of the nuclear envelope. In contrast to many fungi, the corn smut fungus Ustilago maydis also removes the nuclear envelope.
Theisen, Ulrike +2 more
core +1 more source
Studying Kinetochore Kinases [PDF]
, 2016 Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions.
Saurin, Adrian T., Kops, Geert J. P. L.
openaire +4 more sources
Balancing the kinetochore ledger [PDF]
Journal of Cell Biology, 2012 Reduction of polo-like kinase-1 (Plk1) at kinetochores as cells progress from prometaphase to metaphase is surprising given that the kinase is thought to stabilize kinetochore–microtubule (kt–MT) attachments. In this issue, Liu et al. (2012. J. Cell Biol.
Cane, Stuart, Maresca, Thomas J.
openaire +2 more sources
Importin-beta and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function [PDF]
, 2017 Protein conjugation with small ubiquitin-related modifier (SUMO) is a post-translational modification that modulates protein interactions and localisation.
Damizia, Michela +7 more
core +1 more source
A satellite explosion in the genome of holocentric nematodes. [PDF]
PLoS ONE, 2013 Centromere sequences in the genome are associated with the formation of kinetochores, where spindle microtubules grow in mitosis. Centromere sequences usually have long tandem repeats (satellites).
Juan A Subirana, Xavier Messeguer
doaj +1 more source
Feedback control of PLK1 by Apolo1 ensures accurate chromosome segregation
Cell Reports, 2021 Summary: Stable transmission of genetic material during cell division requires accurate chromosome segregation. PLK1 dynamics at kinetochores control establishment of correct kinetochore-microtubule attachments and subsequent silencing of the spindle ...
Leilei Xu +21 more
doaj +1 more source
A novel chromosome segregation mechanism during female meiosis. [PDF]
, 2016 In a wide range of eukaryotes, chromosome segregation occurs through anaphase A, in which chromosomes move toward stationary spindle poles, anaphase B, in which chromosomes move at the same velocity as outwardly moving spindle poles, or both. In contrast,
Cortes, Daniel B +4 more
core +1 more source