Results 81 to 90 of about 20,432 (180)

Dynamics and control of sister kinetochore behavior during the meiotic divisions in Drosophila spermatocytes. [PDF]

PLoS Genetics, 2018
Sister kinetochores are connected to the same spindle pole during meiosis I and to opposite poles during meiosis II. The molecular mechanisms controlling the distinct behavior of sister kinetochores during the two meiotic divisions are poorly understood.
Soumya Chaurasia, Christian F Lehner
doaj   +1 more source

Role for polo-like kinase 4 in mediation of cytokinesis. [PDF]

, 2019
The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes.
Brugge, Joan S, Davenport, Simon, Guzman, Roberta, Mak, Tak W, Nolan, Garry P, O'Brien, Neil, Palazzolo, Michael, Press, Michael F, Slamon, Dennis J, Xie, Bin, Zhou, Yu   +10 more
core   +2 more sources

Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

eLife, 2014
To protect against aneuploidy, chromosomes must attach to microtubules from opposite poles (‘biorientation’) prior to their segregation during mitosis.
Kitty F Verzijlbergen, Olga O Nerusheva, David Kelly, Alastair Kerr, Dean Clift, Flavia de Lima Alves, Juri Rappsilber, Adele L Marston   +7 more
doaj   +1 more source

Tethering sister centromeres to each other suggests the spindle checkpoint detects stretch within the kinetochore. [PDF]

PLoS Genetics, 2014
The spindle checkpoint ensures that newly born cells receive one copy of each chromosome by preventing chromosomes from segregating until they are all correctly attached to the spindle.
Natalie J Nannas, Andrew W Murray
doaj   +1 more source

Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection [PDF]

, 2016
Indexación: Web of Science.During the early steps of infection, retroviruses must direct the movement of the viral genome into the nucleus to complete their replication cycle.
Arriagada, Gloria, Cancino, Jorge, Goff, Stephen P., Opazo, Tatiana, Valle-Tenney, Roger   +4 more
core   +1 more source

Centromeric Non-Coding RNAs: Conservation and Diversity in Function

Non-Coding RNA, 2020
Chromosome segregation is strictly regulated for the proper distribution of genetic material to daughter cells. During this process, mitotic chromosomes are pulled to both poles by bundles of microtubules attached to kinetochores that are assembled on ...
Takashi Ideue, Tokio Tani
doaj   +1 more source

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα [PDF]

, 2012
© 2012 Samejima et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication dateMitotic chromosome formation involves a relatively minor ...
Adolph, Adolph, Aizawa, Alastair Kerr, Baxter, Baxter, Belmont, Bhat, Bouck, Carol A. Cooke, Carpenter, Castoldi, Chang, Christensen, Christine J. Farr, Cox, Csankovszki, Damien F. Hudson, David A. Kelly, Earnshaw, Earnshaw, Earnshaw, Flavia de Lima Alves, Gasser, Geiman, Gerlich, Giulia Vargiu, Gonzalez, Green, Hagstrom, Heermann, Hirano, Hirano, Hiromi Ogawa, Holm, Hori, Hu, Hudson, Hudson, Hudson, Itaru Samejima, Jaqaman, Johnson, Juri Rappsilber, Kaitna, Kumiko Samejima, Kurasawa, Kwon, Lee, Lewis, Lydia C. Green, MacCallum, Maeshima, Markaki, Marko, Mazumdar, Mazumdar, Mazumdar, Midorikawa, Mora-Bermúdez, Moser, Oh, Ohta, Ohta, Ohta, Oliveira, Ono, Paola Vagnarelli, Phair, Pienta, Rappsilber, Ribeiro, Saitoh, Saka, Sakaguchi, Samejima, Sekine, Shevchenko, Shintomi, Shinya Ohta, Spence, Steffensen, Strunnikov, Takata, Takeda, Tavormina, Tjio, Uemura, Vagnarelli, Vagnarelli, Vagnarelli, Vernos, Waldmann, Wang, William C. Earnshaw, Williams, Wu   +96 more
core   +2 more sources

The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation [PDF]

, 2015
Unlike other organisms that have evolved distinct H2A variants for different functions, Drosophila melanogaster has just one variant which is capable of filling many roles.
Cenci, Giovanni, Verni', Fiammetta
core   +1 more source

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

eLife, 2016
The spindle- and kinetochore-associated (Ska) complex is essential for normal anaphase onset in mitosis. The C-terminal domain (CTD) of Ska1 binds microtubules and was proposed to facilitate kinetochore movement on depolymerizing spindle microtubules ...
Sushama Sivakumar, Paweł Ł Janczyk, Qianhui Qu, Chad A Brautigam, P Todd Stukenberg, Hongtao Yu, Gary J Gorbsky   +6 more
doaj   +1 more source

Holocentric Chromosomes of Luzula elegans Are Characterized by a Longitudinal Centromere Groove, Chromosome Bending, and a Terminal Nucleolus Organizer Region [PDF]

, 2011
The structure of holocentric chromosomes was analyzed in mitotic cells of Luzula elegans. Light and scanning electron microscopy observations provided evidence for the existence of a longitudinal groove along each sister chromatid.
A. Houben, Albertson DG, Albertson DG, Allshire RC, Bizzaro D, Black BE, Black BE, Black BE, Braselton JP, Buchwitz BJ, Carroll CW, Cattani MV, Comings DE, Cox AV, da Silva CR, Dernburg AF, Desai A, E. Schroeder-Reiter, Earnshaw WC, Fuchs J, Fukova I, G. Wanner, Gerlach WL, Guerra M, Guerra M, Houben A, Howe M, K. Kumke, K. Nagaki, Kato A, Kitagawa R, L. Ma, M. Murata, Maddox PS, Madej A, Mandakova T, Mandrioli M, Martin R, Moore LL, Nagaki K, Papeschi AG, Pimpinelli S, Raska I, Rebagliati PJ, S. Heckmann, Schneider MC, Schroeder-Reiter E, Sekulic N, Sullivan KF, Valarik M, Vanzela ALL, Vanzela ALL, Viera A, Wanner G   +53 more
core   +1 more source