Results 111 to 120 of about 5,030 (211)

Corrigendum: Induced expression of kir6.2 in A1 astrocytes propagates inflammatory neurodegeneration via Drp1-dependent mitochondrial fission

Frontiers in Pharmacology, 2023
Nanshan Song, Hong Zhu, Rong Xu, Jiaqi Liu, Yinquan Fang, Jing Zhang, Jianhua Ding, Gang Hu, Gang Hu, Ming Lu, Ming Lu   +10 more
doaj   +1 more source

Abstracts From PVRI 2026 Dublin

Pulmonary Circulation, Volume 16, Issue 2, June 2026.
wiley   +1 more source

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP.

, 1999
ATP-sensitive potassium channels are under complex regulation by intracellular ATP and ADP. The potentiating effect of MgADP is conferred by the sulfonylurea receptor subunit of the channel, SUR, whereas the inhibitory effect of ATP appears to be ...
Proks, P, Ashcroft, FM, Tucker, Stephen, Tucker, SJ, Seino, S, Ueda, K, Matsuo, M, Amachi, T, Tanabe, K, Ashcroft, Frances   +9 more
core   +1 more source

ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer.

, 2004
ATP-sensitive K(+) (K(ATP)) channels play important roles in the regulation of membrane excitability in many cell types. ATP inhibits channel activity by binding to a specific site formed by the N and C termini of the pore-forming subunit, Kir6.2, but ...
Ashcroft, FM, Rutter, GA, Tsuboi, T, Lippiat, JD, Ashcroft, Frances   +4 more
core   +1 more source

Rebuilding a macromolecular membrane complex at the atomic scale: case of the Kir6.2 potassium channel coupled to the muscarinic acetylcholine receptor M2

, 2014
Ion channel-coupled receptors (ICCR) are artificial proteins built from a G protein-coupled receptor and an ion channel. Their use as molecular biosensors is promising in diagnosis and high-throughput drug screening.
Moreau, Christophe J, Vivaudou, Michel, Estrada-Mondragon, Argel, Crouzy, Serge, Sapay, Nicolas, Moreau, Christophe   +5 more
core   +1 more source

Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo.

, 2007
ATP-sensitive potassium (K(ATP)) channels are weak inward rectifiers that appear to play an important role in protecting neurons against ischemic damage.
Sun, HS, French, RJ, Barber, PA, Feng, ZP, Buchan, Alastair, Buchan, AM   +5 more
core   +1 more source

Etude structure-fonction du canal Kir6.2 et de son couplage avec des partenaires naturels et artificiels

, 2015
ATP-sensitive potassium (K-ATP) channels play a key role in adjusting the membrane potential to the metabolic state of cells. They result from the unique combination of two proteins: the SulfonylUrea Receptor (SUR), a protein of the ABC transporters ...
Principalli, Maria Antonietta
core  

Pengaruh Pemberian Protein CSN1S2 terhadap Sekuen Gen Kir6.2 pada Tikus Model Diabetes Melitus Tipe 2 [PDF]

, 2018
Penelitian ini bertujuan untuk menganalisis pengaruh pemberian protein CSN1S2 dari susu kambing peranakan etawah terhadap sekuen gen Kir6.2 pada tikus model DMT2. Hewan coba yang digunakan adalah tikus jantan (Rattus norvegicus strain Wistar) yang dibagi
Meidinna, Hazna Noor
core  

Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2.

, 2018
"With no lysine" (WNK) kinases have been shown to regulate various ion transporters in various tissues, but studies on the function of WNK kinases in the brain have been limited. In this study, we discovered that WNK1 and WNK4 in POMC-expressing neuronal
이민구, 김주영
core   +1 more source

Functional analysis of two Kir6.2 (KCNJ11) mutations, K170T and E322K, causing neonatal diabetes.

, 2007
Heterozygous activating mutations in Kir6.2 (KCNJ11), the pore-forming subunit of the adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channel, are a common cause of neonatal diabetes (ND).
Larkin, B, S. Ellard, Girard, CA, Tammaro, P, C. A. Girard, P. Tammaro, Tarasov, AI, Flanagan, SE, Ashcroft, Frances, Girard, C. A., Ashcroft, FM, Tammaro, P., Flanagan, S. E., F. M. Ashcroft, Larkin, B., A. I. Tarasov, B. Larkin, S. E. Flanagan, Tarasov, A. I., Tammaro, Paolo, Ellard, S, Ellard, S., Ashcroft, Frances M.   +22 more
core   +1 more source