Kisspeptin/Kisspeptin Receptor System in the Ovary [PDF]
Frontiers in Endocrinology, 2018 Kisspeptins are a family of neuropeptides that are critical for initiating puberty and regulating ovulation in sexually mature females via the central control of the hypothalamic–pituitary–gonadal axis.
Kai-Lun Hu +4 more
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#363 : Kisspeptins and Human Reproduction: New Challenges in the Management of Couple Infertility
Fertility & Reproduction, 2023 Background and Aims: Human reproduction is strictly controlled by a complex neurohormonal system including the gonadotropin-releasing hormone (GnRH) production, which stimulates anterior pituitary gonadotropes secretion and thereby gonadal function. Now,
Afifa Sellami +5 more
doaj +2 more sources
Expression of kisspeptins and kiss receptors suggests a large range of functions for kisspeptin systems in the brain of the European sea bass. [PDF]
PLoS ONE, 2013 This study, conducted in the brain of a perciform fish, the European sea bass, aimed at raising antibodies against the precursor of the kisspeptins in order to map the kiss systems and to correlate the expression of kisspeptins, kiss1 and kiss2, with ...
Sebastián Escobar +9 more
doaj +3 more sources
Frontiers in Endocrinology, 2018 The European eel (Anguilla anguilla) presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins.
Jérémy Pasquier +10 more
doaj +2 more sources
Inotropic action of the puberty hormone kisspeptin in rat, mouse and human: cardiovascular distribution and characteristics of the kisspeptin receptor. [PDF]
PLoS ONE, 2011 Kisspeptins, the ligands of the kisspeptin receptor known for its roles in reproduction and cancer, are also vasoconstrictor peptides in atherosclerosis-prone human aorta and coronary artery.
Janet J Maguire +6 more
doaj +5 more sources
Kisspeptins, Estrogens and Male Fertility [PDF]
Current Medicinal Chemistry, 2016 The control of male fertility requires accurate endocrine, paracrine and autocrine communications along the hypothalamus-pituitary-gonad (HPG) axis. In this respect, the possible interplay between upcoming/classical modulators of reproductive functions deserves attention in that may be a successful tool for the future exploitation of new potential ...
CHIANESE, Rosanna +7 more
openaire +4 more sources
Kisspeptin/G protein-coupled receptor-54 system as an essential gatekeeper of pubertal development [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2013 Puberty is the end-point of a complex series of developmental events, defined by the dynamic interaction between genetic factors and environmental cues, ultimately leading to the attainment of reproductive capacity.
Young-Jun Rhie
doaj +2 more sources
Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides [PDF]
BMC Biology, 2022 Background Kisspeptins are neuropeptides that regulate reproductive maturation in mammals via G-protein-coupled receptor-mediated stimulation of gonadotropin-releasing hormone secretion from the hypothalamus.
Nayeli Escudero Castelán +10 more
doaj +2 more sources
Controversial Role of Kisspeptins/KiSS-1R Signaling System in Tumor Development
Frontiers in Endocrinology, 2018 KiSS-1 was first described as a metastasis suppressor gene in malignant melanoma. KiSS-1 encodes a 145 amino-acid residue peptide that is further processed, producing the 54 amino acid metastin and shorter peptides collectively named kisspeptins (KPs ...
Federica Fratangelo +3 more
doaj +3 more sources
Kisspeptins modulate the biology of multiple populations of gonadotropin-releasing hormone neurons during embryogenesis and adulthood in zebrafish (Danio rerio). [PDF]
PLoS ONE, 2014 Kisspeptin1 (product of the Kiss1 gene) is the key neuropeptide that gates puberty and maintains fertility by regulating the gonadotropin-releasing hormone (GnRH) neuronal system in mammals.
Yali Zhao +4 more
doaj +3 more sources