Results 31 to 40 of about 2,088 (213)
Current Perspectives on Kisspeptins Role in Behaviour
Frontiers in Endocrinology, 2022 The neuropeptide kisspeptin is now well-established as the master regulator of the mammalian reproductive axis. Beyond the hypothalamus, kisspeptin and its cognate receptor are also extensively distributed in extra-hypothalamic brain regions.
Edouard G. Mills +6 more
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Kisspeptins - Expression, Purification, and Biological Assays [PDF]
, 2013 Kisspeptins are hormones involved in the onset of puberty in adolescents and maintenance of reproductive function in adults. Defects in kisspeptin signaling are associated with many reproductive disorders.
Kurian, Mathew Puthayathu
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Frontiers in Neuroscience, 2018 Genetic manipulation of teleost endocrine systems started with transgenic overexpression of pituitary growth hormone. Such strategies enhance growth and reduce fertility, but the fish still breed.
Vance L. Trudeau
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Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing. [PDF]
PLoS ONE, 2014 KISS1 is a broadly functional secreted proprotein that is then processed into small peptides, termed kisspeptins (KP). Since sequence analysis showed cleavage at KR or RR dibasic sites of the nascent protein, it was hypothesized that enzyme(s) belonging ...
Sitaram Harihar +4 more
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Effect of Kisspeptin-54 on Testicular Degeneration Induced by Cadmium Chloride [PDF]
Archives of Razi Institute, 2022 Adult males are considered the main causes of infertility defects in the world; therefore, scientists are searching for factors that play a role in male fertility, such as kisspeptin, which acts as one of the master controllers and regulators of ...
M Ali Hameed +3 more
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Tachykinins and Kisspeptins in the Regulation of Human Male Fertility [PDF]
, 2019 Infertility is a global disease affecting one out of six couples of reproductive age in the world, with a male factor involved in half the cases. There is still much to know about the regulation of human male fertility and thus we decided to focus on two
Fernández Sánchez, Manuel +16 more
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Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes. [PDF]
, 2013 Kisspeptins, endogenous peptide ligands for GPR54, play an important role in GnRH secretion. Since in vivo administration of kisspeptins induces increased plasma LH levels, GPR54 agonists hold promise as therapeutic agents for the treatment of hormonal ...
Kaneda, Masato +9 more
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Frontiers in Endocrinology, 2022 Kisspeptin has an important role in the regulation of reproduction by directly stimulating the secretion of gonadotropin-releasing hormone (GnRH) in mammals.
Md. Mahiuddin Zahangir +2 more
doaj +1 more source
Reproductive Medicine, 2022 Insufficient invasion of conceptus-derived trophoblast cells in the maternal decidua is a key event in the development of early-onset preeclampsia (PE), a subtype of PE associated with high maternal and fetal morbidity and mortality.
Viviane C. L. Gomes +9 more
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, 2021 Preeclampsia (PE) is a life-threatening human gestational syndrome with incompletely understood etiopathogenesis. The disorder has a spectrum of clinical features, likely due to a complex interaction between maternal predisposing factors and ...
Sones, Jenny L +5 more
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