Results 31 to 40 of about 1,992 (211)

Facing the Challenges of Neuropeptide Gene Knockouts: Why Do They Not Inhibit Reproduction in Adult Teleost Fish?

open access: yesFrontiers in Neuroscience, 2018
Genetic manipulation of teleost endocrine systems started with transgenic overexpression of pituitary growth hormone. Such strategies enhance growth and reduce fertility, but the fish still breed.
Vance L. Trudeau
doaj   +1 more source

Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing. [PDF]

open access: yesPLoS ONE, 2014
KISS1 is a broadly functional secreted proprotein that is then processed into small peptides, termed kisspeptins (KP). Since sequence analysis showed cleavage at KR or RR dibasic sites of the nascent protein, it was hypothesized that enzyme(s) belonging ...
Sitaram Harihar   +4 more
doaj   +1 more source

Effect of Kisspeptin-54 on Testicular Degeneration Induced by Cadmium Chloride [PDF]

open access: yesArchives of Razi Institute, 2022
Adult males are considered the main causes of infertility defects in the world; therefore, scientists are searching for factors that play a role in male fertility, such as kisspeptin, which acts as one of the master controllers and regulators of ...
M Ali Hameed   +3 more
doaj   +1 more source

Tachykinins and Kisspeptins in the Regulation of Human Male Fertility [PDF]

open access: yes, 2019
Infertility is a global disease affecting one out of six couples of reproductive age in the world, with a male factor involved in half the cases. There is still much to know about the regulation of human male fertility and thus we decided to focus on two
Fernández Sánchez, Manuel   +16 more
core   +1 more source

From inhibition of trophoblast cell invasion to proapoptosis: what are the potential roles of kisspeptins in preeclampsia?

open access: yes, 2021
Preeclampsia (PE) is a life-threatening human gestational syndrome with incompletely understood etiopathogenesis. The disorder has a spectrum of clinical features, likely due to a complex interaction between maternal predisposing factors and ...
Sones, Jenny L   +3 more
core   +1 more source

Kisspeptin/G protein-coupled receptor-54 system as an essential gatekeeper of pubertal development [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2013
Puberty is the end-point of a complex series of developmental events, defined by the dynamic interaction between genetic factors and environmental cues, ultimately leading to the attainment of reproductive capacity.
Young-Jun Rhie
doaj   +1 more source

Kisspeptin Exhibits Stimulatory Effects on Expression of the Genes for Kisspeptin Receptor, GnRH1 and GTH Subunits in a Gonadal Stage-Dependent Manner in the Grass Puffer, a Semilunar-Synchronized Spawner

open access: yesFrontiers in Endocrinology, 2022
Kisspeptin has an important role in the regulation of reproduction by directly stimulating the secretion of gonadotropin-releasing hormone (GnRH) in mammals.
Md. Mahiuddin Zahangir   +2 more
doaj   +1 more source

Kisspeptin Is Upregulated at the Maternal-Fetal Interface of the Preeclamptic-like BPH/5 Mouse and Normalized after Synchronization of Sex Steroid Hormones

open access: yesReproductive Medicine, 2022
Insufficient invasion of conceptus-derived trophoblast cells in the maternal decidua is a key event in the development of early-onset preeclampsia (PE), a subtype of PE associated with high maternal and fetal morbidity and mortality.
Viviane C. L. Gomes   +9 more
doaj   +1 more source

Kisspeptins

open access: yes, 2013
Manuel Tena-Sempere
openaire   +2 more sources

Characterization of the receptor binding residues of kisspeptins by positional scanning using peptide photoaffinity probes. [PDF]

open access: yes, 2013
Kisspeptins, endogenous peptide ligands for GPR54, play an important role in GnRH secretion. Since in vivo administration of kisspeptins induces increased plasma LH levels, GPR54 agonists hold promise as therapeutic agents for the treatment of hormonal ...
Kaneda, Masato   +9 more
core   +1 more source

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