Results 51 to 60 of about 2,088 (213)
Comparison of the effects of peripherally administered kisspeptins
, 2008 Kisspeptins are structurally closely related peptides derived from the Kiss1 gene that have been demonstrated to stimulate the hypothalamo-pituitary gonadal axis.
Bentsen, Agnete H +4 more
core +1 more source
Interactions between prolactin and kisspeptin to control reproduction
Archives of Endocrinology and Metabolism, 2016 Prolactin is best known for its effects of stimulating mammary gland development and lactogenesis. However, prolactin is a pleiotropic hormone that is able to affect several physiological functions, including fertility.
Jose Donato Jr., Renata Frazão
doaj +1 more source
An update on the genetic causes of central precocious puberty [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2016 Central precocious puberty (CPP) is caused by the premature reactivation of the hypothalamic-pituitary-gonadal axis. Genetic, nutritional, and environmental factors play a crucial role in determining pubertal timing.
Young-Lim Shin
doaj +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To investigate the factors associated with non‐vasomotor menopause symptoms among women in the UK, focusing on the perceived importance of specific symptoms and their association with demographic and treatment‐related factors. Design A cross‐sectional online survey.
Rhianna Davies +12 more
wiley +1 more source
Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets
, 2009 Islet hormone secretion is regulated by a variety of factors, and many of these signal through G protein-coupled receptors (GPCRs). A novel islet GPCR is GPR54, which couples to the Gq isoform of G proteins, which in turn signal through the phospholipase
Vikman, Jenny, +2 more
core +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber +7 more
wiley +1 more source
Deregulation of miR-324/KISS1/kisspeptin in early ectopic pregnancy: mechanistic findings with clinical and diagnostic implications [PDF]
, 2019 BACKGROUND: Ectopic pregnancy is a life-threatening condition for which novel screening tools that would enable early accurate diagnosis would improve clinical outcomes.
A., Romero-Ruiz +16 more
core +3 more sources
Does kisspeptin signalling have a role in the testes?
Frontiers in Endocrinology, 2013 Kisspeptins are a family of overlapping neuropeptides encoded by the Kiss1 gene that regulate the mammalian reproductive axis by a central action in the hypothalamus to stimulate GnRH release. Kisspeptins and their receptor (Gpr54 also called Kiss1r) are
Mei eHua +4 more
doaj +1 more source
Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes
Experimental Physiology, EarlyView.Abstract Hot flushes of menopause are associated with elevated blood pressure (BP) and diminished macrovascular endothelial function, an initiating factor in the onset of atherosclerosis. Whether microvascular endothelial function is impaired in females with hot flushes, however, remains unknown.
William Stokes +9 more
wiley +1 more source
Seasonal Variation in the Gonadotropin-Releasing Hormone Response to Kisspeptin in Sheep: Possible Kisspeptin Regulation of the Kisspeptin Receptor [PDF]
Neuroendocrinology, 2012 Kisspeptin signaling in the hypothalamus appears critical for the onset of puberty and driving the reproductive axis. In sheep, reproduction is seasonal, being activated by short days and inhibited by long days. During the non-breeding (anestrous) season, gonadotropin-releasing hormone (GnRH) and gonadotropin secretion is reduced, as is the expression ...
Qun, Li +3 more
openaire +2 more sources