Results 71 to 80 of about 2,088 (213)
Body fat distribution was associated with vasomotor symptoms in a menopausal stage‐specific manner. Greater trunk and abdominal adiposity were linked to more frequent and bothersome symptoms during perimenopause, whereas distinct abdominal adiposity measures showed contrasting associations with symptom burden after menopause.
Katarzyna Górecka, Monika Krzyżanowska
wiley +1 more source
Kisspeptin, encoded by the KISS1 gene, was first discovered as a potential metastasis suppressor gene. The prepro-kisspeptin precursor is cleaved into shorter mature bioactive peptides of varying sizes that bind to the G protein-coupled receptor GPR54 (=KISS1R).
Mageswary Sivalingam, Ishwar S. Parhar
openaire +2 more sources
Expression of kisspeptins in the brain and pituitary of the european sea bass (Dicentrarchus labrax)
Kisspeptins are now considered key players in the neuroendocrine control of puberty and reproduction, at least in mammals. Most teleosts have two kiss genes, kiss1 and kiss2, but their sites of expression are still poorly documented.
Zanuy, Silvia +6 more
core +1 more source
Abstract Premature ovarian insufficiency (POI) and early menopause (EM) affect millions of women worldwide. Compared with normal menopause, they confer a longer duration of estrogen deficiency and are associated not only with a shorter lifespan, but with a reduced healthspan, owing to an increased risk of cardiovascular, skeletal, cognitive and ...
Chiara Benedetto +8 more
wiley +1 more source
Previous studies have shown the regulation of follicle-stimulating hormone (Fshβ) and luteinizing hormone (Lhβ) during early ovarian differentiation and development from 30 to 160 days post-hatching (dph) in the red-spotted grouper.
Wengang Xu +3 more
doaj +1 more source
Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men [PDF]
Kisspeptins stimulate GnRH and thus gonadotropin secretion. Kisspeptin-10 is the minimal kisspeptin sequence with full intrinsic bioactivity, but it has not been studied in ...
Anderson, Richard A. +20 more
core +1 more source
Kisspeptins are involved in the regulation of hypothalamic-pituitary-gonadal axis, Leydig cell functions, and testosterone secretion, acting as endogenous ligands of the KISS1 receptor.
Giulia Ricci +12 more
doaj +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Kisspeptin and Clinical Disorders [PDF]
The hypothalamic hormone GnRH has traditionally been viewed as a central driver of the hypothalamic-pituitary-gonadal axis. Pulsatile GnRH release is required for pulsatile gonadotropin secretion, which then modulates gonadal steroid feedback and brings about full fertility in the adult.
Letícia Gontijo, Silveira +2 more
openaire +2 more sources
IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente +17 more
wiley +1 more source

