Results 81 to 90 of about 402 (139)

Neuroendocrine Mechanisms Regulating Reproductive Transition in the Ruminant Female: Is KNDy Required?

Journal of Animal Science, 2021
Abstract States of reproductive transition in female livestock represent important and economically significant periods of physiological change that have major impacts on the efficiency and success of breeding and production programs.
openaire   +1 more source

Envolvimento dos neurônios KNDy na dissipação de calor causada pela deficiência de esteroides sexuais em ratos machos e fêmeas [PDF]

, 2022
Hot flashes consist of a disorder in thermoregulation, characterized by peripheral vasodilation and increased heat dissipation, caused by reduced levels of estradiol (E2) in the postmenopausal period.
Kaoma Stephani da Costa Silva
core  

Regulação dos neurônios KNDy pelo estradiol: papel da kisspeptina e dinorfina no controle da secreção de prolactina e hormônio luteinizante [PDF]

, 2017
Kisspeptin, neurokinin and dynorphin (KNDy) neurons in the arcuate nucleus (ARC) are implicated in luteinizing hormone (LH) pulsatility. Previous evidence has also shown that KNDy neurons have extensive projections onto tuberoinfundibular dopaminergic ...
Roberta Araújo Lopes
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The regulation of reproduction by glutamatergic signaling from KNDy neurons [PDF]

BACKGROUND: Two major populations of kisspeptin-expressing neurons in the hypothalamus synapse onto the gonadotropin-releasing hormone (GnRH) neurons to control the secretion of GnRH and, therefore, the luteinizing hormone (LH) and follicle-stimulating ...
Medve, Elizabeth
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Microglia as candidate links between hormonal signals and neuronal circuits in polycystic ovary syndrome: evidence gaps and a research agenda

Frontiers in Endocrinology
Polycystic ovary syndrome (PCOS) combines reproductive endocrine dysfunction with metabolic, autonomic, and neurobehavioral phenotypes, yet the contribution of brain microglia remains uncertain.
Hongtao Li, Tong Yin, Yichen Wang, Yixuan Wang, Xiaoyuan Lin, Xinyan Jia, Wei Yi, Han Yang, Han Yang   +8 more
doaj   +1 more source

Deletion of arcuate nucleus-specific Kiss1 disrupts estrous cyclicity and LH pulsatility in female mice

, 2020
Kisspeptin (encoded by Kiss1), a neuropeptide critically involved in neuroendocrine regulation of reproduction, is primarily synthesized in two discrete hypothalamic nuclei: the anteroventral periventricular nucleus (AVPV) and arcuate nucleus (ARC ...

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Fezolinetant- A novel NK3R antagonist for treating postmenopausal vasomotor symptoms

Journal of the Pakistan Medical Association
Madam, It has been estimated that up to 80% of postmenopausal women experience vasomotor symptoms (VMS) such as hot flushes, night sweats, mood swings and difficulty in concentrating1. These symptoms markedly affect different aspects of daily life for
Saqib Ali, Muhammad Affan Ilyas
doaj   +1 more source

Influence of Age and 17β-Estradiol on Kisspeptin, Neurokinin B, and Prodynorphin Gene Expression in the Arcuate-Median Eminence of Female Rhesus Macaques

, 2010
The neuropeptides kisspeptin, neurokinin B, and dynorphin A (collectively abbreviated as KNDy) are, respectively, encoded by KiSS-1, NKB, and PDYN and are coexpressed by neurons of the hypothalamic arcuate nucleus (ARC).
Dominique H. Eghlidi, Steven G. Kohama, Gwendolen E. Haley, Nigel C. Noriega, Henryk F. Urbanski   +4 more
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7441 KNDy Neurons and the Control of the Gonadotropic Axis in Midgestation Fetal Sheep

Journal of the Endocrine Society
Abstract Disclosure: R. Amodei: None. S.S. Jonker: None. K. Gribbin: None. E. Lazen: None. C.T. Estill: None. C.E. Roselli: None. Recent evidence suggests that the neuropeptide kisspeptin (Kiss) plays a role to activate and regulate the male reproductive axis to secrete LH and testosterone during a time in gestation ...
Amodei, R, Jonker, S S, Gribbin, K, Lazen, E, Estill, C T, Roselli, C E   +5 more
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Sex-specific differences in mediobasal hypothalamus in response to nutritional states

Nature Communications
The arcuate nucleus of the hypothalamus plays a central role in sensing and integrating nutritional, hormonal, and neural signals that regulate feeding, energy homeostasis, growth, and reproduction, all of which show pronounced sex differences.
Jonathan C. Bean, Jinjing Jian, Tzu-Chiao Lu, Hailan Liu, Kristine Conde, Darah A. Threat, Sanika V. Jossy, Megan E. Burt, Jingjing Cheng, Yue Deng, Xing Fang, Xiaoyu Geng, Junying Han, Yongxiang Li, Hesong Liu, Qingzhuo Liu, Yutian Liu, Yuhan Shi, Longlong Tu, Mengjie Wang, Xu Xu, Yuxue Yang, Meng Yu, Xinming Liu, Meixin Sun, Fuhui Wang, Olivia Z. Ginnard, Yongjie Yang, Yang He, Chunmei Wang, Yanyan Qi, Hongjie Li, Yong Xu   +32 more
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