Results 11 to 20 of about 3,537 (198)

Environmental Influence on the Untargeted Foliar Metabolome of Naturally Growing Mitragyna Species in Thailand. [PDF]

open access: yesPlant Environ Interact
ABSTRACT This study investigates the foliar secondary metabolite profiles of four Mitragyna species naturally occurring in Thailand: M. diversifolia, M. hirsuta, M. rotundifolia, and M. speciosa (kratom). Using untargeted gas chromatography–mass spectrometry (GC–MS), 409 secondary volatile metabolites were annotated across the four species.
Andriyas T   +5 more
europepmc   +2 more sources

Kratom-Associated Diffuse Alveolar Haemorrhage: A Clinical Image. [PDF]

open access: yesRespirol Case Rep
We report the case of a patient who developed diffuse alveolar haemorrhage shortly after heavy kratom ingestion. Imaging and bronchoscopy confirmed haemorrhage. Vaping was excluded as a confounder. ABSTRACT A patient developed diffuse alveolar haemorrhage shortly after heavy kratom ingestion. Imaging and bronchoscopy confirmed haemorrhage.
Kanchustambham V, Johnson K.
europepmc   +2 more sources

Kratom use disorder and unfolded protein response: Evaluating their relationship in a case control study.

open access: yesPLoS ONE, 2023
Background and aimsKratom (Mitragyna speciosa Korth.) is widely use worldwide despite its addictive potential. Although psychostimulant use has been linked to occurrence of endoplasmic reticulum (ER) stress, data is lacking on how regular kratom use ...
Bin Yang   +4 more
doaj   +1 more source

The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation

open access: yesFrontiers in Pharmacology, 2021
Mitragyna speciosa (“kratom”), employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America.
Shoshana Buckhalter   +12 more
doaj   +1 more source

Biosynthesis of Kratom Opioids

open access: yesNew Phytologist, 2022
AbstractMitragyna speciosa(kratom) derived monoterpenoid indole alkaloids (MIAs) such as mitragynine and 7-hydroxymitragynine are a new class of opioids with a corynanthe MIA pharmacophore that is responsible for their significantly reduced side effects and superior safety profiles.
Kyunghee Kim   +6 more
openaire   +2 more sources

Searching for a Signal: Self-Reported Kratom Dose-Effect Relationships Among a Sample of US Adults With Regular Kratom Use Histories

open access: yesFrontiers in Pharmacology, 2022
There is limited understanding regarding kratom use among US adults. Although motivations for use are increasingly understood, typical kratom doses, threshold of (low and high) doses for perceived effectiveness, and effects produced during cessation are ...
Kirsten E. Smith   +6 more
doaj   +1 more source

The cellular toxicology of mitragynine, the dominant alkaloid of the narcotic-like herb, Mitragyna speciosa Korth [PDF]

open access: yes, 2015
Mitragyna speciosa Korth (Kratom), a herb of the Rubiaceae family is indigenous in southeast Asia mainly in Malaysia and Thailand. It is used as an opium substitute and has been increasingly abused by drug addicts in Malaysia.
Gooderham, NJ   +3 more
core   +5 more sources

High serum high-density lipoprotein and low serum triglycerides in Kratom users: A study of Kratom users in Thailand

open access: yesHeliyon, 2021
Objective: The present study aims to examine the association between Kratom use and serum lipid level. Method: This study compared the serum lipid profile of Kratom users and non-users living in Nam Phu Subdistrict, a special area that allows the ...
Aroon La-up   +2 more
doaj   +1 more source

An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021

open access: yesClinical and Translational Science, 2023
Kratom is a widely used Asian botanical that has gained popularity in the United States due to a perception that it can treat pain, anxiety, and opioid withdrawal symptoms. The American Kratom Association estimates 10–16 million people use kratom. Kratom‐
Xiaotong Li   +8 more
doaj   +1 more source

Kratom availability in California vape shops

open access: yesPreventive Medicine Reports, 2023
Kratom products are derived from trees native to Southeast Asia and have dose-dependent stimulant and opioid-like effects. Despite being on the Drug Enforcement Administration “Drugs and Chemicals of Concern List,” kratom is legal for sale in most US ...
Molly A. Bowdring   +5 more
doaj   +1 more source

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