Results 91 to 100 of about 5,262 (204)
Neuroprotection, Volume 3, Issue 4, Page 336-352, December 2025.Workflow of literature screening, bibliometric analysis, and core target identification. Publications on neuroinflammation in central nervous system disorders related to network pharmacology were retrieved from the Web of Science Core Collection. After applying inclusion and exclusion criteria, 156 eligible studies were analyzed.
Yifeng Zhang +7 more
wiley +1 more source
Toxins, 2014 Molecular dynamics (MD) simulations are used to examine the binding modes of two scorpion toxins, margatoxin (MgTx) and hongotoxin (HgTx), to the voltage gated K+ channel, Kv1.3. Using steered MD simulations, we insert either Lys28 or Lys35 of the toxins
Rong Chen, Shin-Ho Chung
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +86 more
wiley +1 more source
Expression von Kv1.3-Kaliumkanälen in retinalen Pigmentepithelzellen [PDF]
, 2007 In vorliegender Arbeit wurde mit Hilfe einer immunhistochemischen Nachweismethode die Expression von Kv1.3-Kaliumkanälen in retinalen Pigmentepithelzellen in vivo und in vitro untersucht. Hierbei wurden unterschiedliche Kulturbedingungen verglichen. Es
Farah, Amin
core
Signalling pathways involved in Kv1.3-induced proliferation
, 2017 Resumen del trabajo presentado al VI Meeting de la Red Española de Canales Ióniocs (RECI), celebrado en Santiago de Compostela del 6 al 8 de septiembre de 2017.Vascular smooth muscle cells (VSMCs) have the ability to switch from a contractile to a ...
Alonso, Esperanza +5 more
core +1 more source
Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel
Scientific Reports, 2016 AbstractThe potassium channel Kv 1.3 plays a vital part in the activation of T lymphocytes and is an attractive pharmacological target for autoimmune diseases. BmP02, a 28-residue peptide isolated from Chinese scorpion (Buthus martensi Karsch) venom, is a potent and selective Kv1.3 channel blocker.
B. Wu +4 more
openaire +2 more sources
Eplerenone Reverses Cardiac Fibrosis via the Suppression of Tregs by Inhibition of Kv1.3 Channel
Frontiers in Physiology, 2018 Background: Fibroblast proliferation is a critical feature during heart failure development. Previous studies reported regulatory T-lymphocytes (Tregs)’ protective role against myocardial fibrosis. However, notably, Tregs also secrete fibrogenic cytokine
Pei-Pei Shao +7 more
doaj +1 more source
Kv1.3 expression on human primary T cell subsets.
, 2017 Kv1.3 expression on human primary T cell subsets.
Yi Liu (36759) +9 more
core +1 more source
BMC Neuroscience, 2009 Background Neurotrophins are important regulators of growth and regeneration, and acutely, they can modulate the activity of voltage-gated ion channels.
Marks David R +4 more
doaj +1 more source
Regulation of Kv1.3 during Fas-Induced Apoptosis
Cellular Physiology and Biochemistry, 1997 Programmed cell death has been shown to be crucial for the regulation of cellular homeostasis. Ligation of CD95 (Apo-1/ Fas) antigen triggers apoptosis by activating an extensively studied signaling ...
SZABO', ILDIKO', Gulbins, E., Lang, F.
openaire +2 more sources