Results 131 to 140 of about 5,991 (236)

Histone Lactylation in Diseases: Regulation by Traditional Chinese Medicine and Therapeutic Implications

Drug Design, Development and Therapy
Yuyue Qiu, Xiaoni Shao College of Pharmacy and Food, Southwest Minzu University, Chengdu, Sichuan, 610225, People’s Republic of ChinaCorrespondence: Xiaoni Shao, College of Pharmacy and Food, Southwest Minzu University, #168 Dajian Street ...
Qiu Y, Shao X
doaj  

Prognostic and therapeutic response prediction in glioblastoma multiforme using a lactylation-associated gene signature

Discover Oncology
Background Glioblastoma (GBM) is a highly aggressive brain tumor characterized by immunosuppressive tumor microenvironment and metabolic reprogramming. Dysregulated lactate metabolism has been observed in the glioma microenvironment, yet the functional ...
Huan Zhu, Guanjun Li, Tingting Li, Xiangdi Yang, Yongqin Yang, Yifei Li, Zhigang Liu   +6 more
doaj   +1 more source

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review). [PDF]

Int J Mol Med
Zhang T, Zhang X, Xie Y, Liu Y, Xia S, Yin X, Li T, Liao L.   +7 more
europepmc   +1 more source

Lactylation Modification: From Basic Biological Process to Clinical Cardiovascular Diseases. [PDF]

Research (Wash D C)
Geng J, Fang Z, Zhang Z, Ge J, Li H.
europepmc   +1 more source

Research progress on the regulation of microglia and astrocyte functions by protein lactylation in cerebral ischemia-reperfusion injury: A review. [PDF]

Medicine (Baltimore)
Song HH, Jiang XC.
europepmc   +1 more source

Lactate and lactylation: metabolic architects of tumor progression and metastasis. [PDF]

Cell Oncol (Dordr)
Ma H, Gu Z, Wang Z.
europepmc   +1 more source

Epigenetic Changes Associated With Obesity-related Metabolic Comorbidities [PDF]

Obesity arises from a complex interaction of genetic, hormonal, dietary, and behavioral factors that drive chronic energy imbalance, excessive fat accumulation, systemic inflammation, and insulin resistance, thus increasing the risk of metabolic diseases.

core   +1 more source

Histone lactylation maintains bovine early embryo development via regulating embryonic genome activation. [PDF]

J Anim Sci Biotechnol
Yu W, Xia Y, Wang W, Yang Z, Liu Z, Gan X, Zhang M, Zhou B, Li Y, Zhang Y, Cao Z.   +10 more
europepmc   +1 more source

Role and clinical importance of lactylation in tumors (Review). [PDF]

Mol Med Rep
Zhang C, Tang X, Han Y, Yao W, Hong Q, Zhu Y, Chen N.   +6 more
europepmc   +1 more source

Hypertension Drives Protein Lactylation and Vascular Dysfunction in Skeletal Muscle. [PDF]

Hypertension
Fontes MT, Townsend P, Butler L, Parente JM, Araujo FA, Costa TJ, Bomfim GF, Pernomian L, Tan W, VanderVeen BN, Murphy EA, Stark RJ, Butcher JT, McCarthy CG, Wenceslau CF.   +14 more
europepmc   +1 more source