Results 171 to 180 of about 7,170 (205)

Uncovering ubiquitous protein lactylation

Nature Methods, 2022
Xiaofeng Wu, W. Andy Tao
openaire   +2 more sources

Global Profiling of Lactylation Proteomics and Specific Lactylated Site Validation in Rheumatoid Arthritis Patients

Journal of Proteome Research
Protein lactylation is a novel post-translational modification that has rarely been investigated in rheumatoid arthritis (RA). This study aimed to explore lactylation proteomics in RA patients and validate sorted candidate lactylation sites. Synovial tissues from ten RA and six osteoarthritis (OA) patients were subjected to lactylation proteomics via ...
Jiaqi Hu, Zhengyi Jin, Ying Gao, Qilong Liu, Yiyi Yu, Ruina Kong, Dongbao Zhao, Jie Gao   +7 more
openaire   +2 more sources

Positive Feedback Regulation of Microglial Glucose Metabolism by Histone H4 Lysine 12 Lactylation in Alzheimer’s Disease

Cell Metabolism, 2022
Zengqiang Yuan, Ju Gao, Lin He
exaly  

Hexokinase 2-Mediated Gene Expression via Histone Lactylation Is Required for Hepatic Stellate Cell Activation and Liver Fibrosis

Cell Metabolism, 2023
Nissim Hay, Constantinos Chronis, Alexander R Terry   +2 more
exaly  

lactyl, n.

2023
openaire   +1 more source

Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction

Circulation Research, 2022
Maomao Zhang, Ping Sun, Naixin Wang
exaly  

Histone Lactylation: Epigenetic Mark of Glycolytic Switch

Trends in Genetics, 2022
Xiaofeng Dai, Kostya Ostrikov, Erik W. Thompson   +2 more
exaly  

Efficient synthesis of lactylated histone peptides enabled by a pre-prepared protected lactylated-lysine

Tetrahedron Letters, 2023
Qingyao Shu, Jian Fan, Bingji Wang, Jing Shi   +3 more
openaire   +1 more source

Role of TFEB lactylation

Nature Cell Biology
openaire   +2 more sources

Biochemistry and Regulation of Histone Lysine l-Lactylation

Nature Reviews Molecular Cell Biology
Philip A Cole, Hening Lin, Xinlei Sheng
exaly