Results 1 to 10 of about 2,786 (146)

α-Tocopherol modulates the low density lipoprotein receptor of human HepG2 cells [PDF]

Nutrition Journal, 2003
The aim of this study was to determine the effects of vitamin E (α-tocopherol) on the low density lipoprotein (LDL) receptor, a cell surface protein which plays an important role in controlling blood cholesterol. Human HepG2 hepatoma cells were incubated
Bottema Cynthia DK, Thomson Andrew M, Pal Sebely, Roach Paul D   +3 more
doaj   +3 more sources

Plasma lathosterol measures rates of cholesterol synthesis and efficiency of dietary phytosterols in reducing the plasma cholesterol concentration

Clinics, 2022
Objectives Because the plasma campesterol/cholesterol ratio does not differ between groups that absorb different amounts of cholesterol, the authors investigated whether the plasma Phytosterols (PS) relate to the body's cholesterol synthesis rate ...
Valéria Sutti Nunes, Angela de Oliveira Godoy Ilha, Guilherme da Silva Ferreira, Renata de Paula Assis Bombo, Milessa Silva Afonso, Maria Silvia Ferrari Lavrador, Roberta Marcondes Machado, Edna Regina Nakandakare, Eder Carlos Rocha Quintão, Ana Maria Lottenberg   +9 more
doaj   +1 more source

Markers of cholesterol synthesis to cholesterol absorption across the spectrum of non‐dialysis CKD: An observational study

Pharmacology Research & Perspectives, 2021
In dialysis patients, cholesterol‐lowering therapy with statins is less effective than in other high‐risk patients. This may be explained by a shift from cholesterol synthesis toward cholesterol absorption. In line, markers of cholesterol absorption—such
Insa E. Emrich, Gunnar H. Heine, P. Christian Schulze, Kyrill S. Rogacev, Danilo Fliser, Stefan Wagenpfeil, Michael Böhm, Dieter Lütjohann, Oliver Weingärtner   +8 more
doaj   +1 more source

Presence of Cholesterol in Non-Animal Organisms: Identification and Quantification of Cholesterol in Crude Seed Oil from Perilla frutescens and Dehydrated Pyropia tenera

Molecules, 2021
Studies have reported that cholesterol, a molecule found mainly in animals, is also present in some plants and algae. This study aimed to determine whether cholesterol exists in three dehydrated algae species, namely, Pyropia tenera, Saccharina japonica,
Min-Ji Oh, Hee-Jin So, Eun-Sik Hong, Jung-Ah Shin, Ki-Teak Lee   +4 more
doaj   +1 more source

Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells [PDF]

, 2008
Besnoitia besnoiti, an apicomplexan parasite of cattle being considered as emergent in Europe, replicates fast in host endothelial cells during acute infection and is in considerable need for energy, lipids and other building blocks for offspring ...
Silva, Liliana M. R., Lütjohann, Dieter, Hamid, Penny, Velasquez, Zahady D., Kerner, Katharina, Larrazabal, Camilo, Failing, Klaus, Hermosilla, Carlos, Taubert, Anja   +8 more
core   +2 more sources

Serum lathosterol levels in human subjects reflect changes in whole body cholesterol synthesis induced by lovastatin but not dietary cholesterol.

Journal of Lipid Research, 1995
We measured serum lathosterol levels and whole body cholesterol synthesis by sterol balance in 12 human subjects on a metabolic ward in four randomly allocated, 6-7 week periods: 1) lovastatin (40 mg b.i.d.) + low cholesterol diet (mean 246 mg/day); 2 ...
W C Duane
doaj   +1 more source

Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population. [PDF]

, 2014
BACKGROUND: The modifications of cholesterol metabolism associated with aging are ill-defined. The objective of this study was to define age-associated alterations of the different metabolic pathways controlling cholesterol homeostasis by analyzing ...
Anzivino C, BALDELLI, Enrica, BERTOLOTTI, Marco, Carulli N., CARULLI, Lucia, Del Puppo M, LORIA, Paola, Magni A, MUSSI, Chiara, OGNIBENE, Silvia, Pellegrini E   +10 more
core   +1 more source

Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans.

Journal of Lipid Research, 1988
The power of serum lathosterol concentration as an indicator of whole-body cholesterol synthesis was investigated in 47 human volunteers consuming two diets differing in fatty acid composition. The cholesterol balance (fecal excretion of neutral and acid
H J Kempen, J F Glatz, J A Gevers Leuven, H A van der Voort, M B Katan   +4 more
doaj   +1 more source

Evaluation of the use of serum lathosterol concentration to assess whole-body cholesterol synthesis in rabbits.

Journal of Lipid Research, 1992
Serum lathosterol concentration in rabbits was assessed as a possible indicator of whole-body cholesterol synthesis. In random-bred New Zealand White (NZW) rabbits fed a control diet or a diet containing either cholesterol, simvastatin, or cholestyramine,
GW Meijer, JG Van der Palen, H De Vries, HJ Kempen, HA Van der Voort, LF Van Zutphen, AC Beynen   +6 more
doaj   +1 more source

High levels of plant sterols and cholesterol precursors in cerebrotendinous xanthomatosis.

Journal of Lipid Research, 1991
We measured the cholestanol, cholesterol precursor (lathosterol), and plant sterol (campesterol and sitosterol) concentrations of serum and bile in 11 patients with cerebrotendinous xanthomatosis.
M Kuriyama, J Fujiyama, T Kasama, M Osame   +3 more
doaj   +1 more source