Results 21 to 30 of about 2,855 (207)

Plasma Levels of Lathosterol and Phytosterols in Relation to Age, Sex, Anthropometric Parameters, Plasma Lipids and Apolipoprotein E Phenotype in 160 Dutch Families [PDF]

, 1991
In this study, the relation of plasma levels of lathosterol (an indicator of whole body cholesterol synthesis) and plant sterols (indicator of cholesterol absorption) with age, sex, weight, height, plasma lipids, and lipoproteins, and with apolipoprotein
Alberts, Assmann, Bjorkhem, Endo, Friedewald, Frishman, Goodman, Gylling, Havekes, Havel, Kempen, Kesaniemi, Lopes-Virella, Miettinen, Miettinen, Miettinen, Miettinen, Nestel, Palmer, Sing, Smit, Stasse-Wolthuis, Tilvis, Utermann   +23 more
core   +1 more source

Long-term effects of sterol depletion in C. elegans

Journal of Lipid Research, 2004
Three major long-term effects of sterol deprivation in Caenorhabditis elegans are described. 1) The life expectancy of sterol-deprived wild-type animals is decreased by more than 40%. Similar decreases are found in animals carrying mutations in the daf-9,
Mark Merris, Jessica Kraeft, G.S. Tint, John Lenard   +3 more
doaj   +1 more source

Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis

Journal of Atherosclerosis and Thrombosis, 2023
Risk of cardiovascular disease is increased in patients with diabetes mellitus (DM). Cholesterol metabolism (hepatic synthesis and intestinal absorption) is known to be associated with cardiovascular risk. Next, we examined the association of DM with cholesterol absorption/synthesis.The CACHE Consortium, which is comprised of 13 research groups in ...
Matsumura, Takeshi, Ishigaki, Yasushi, Nakagami, Tomoko, Akiyama, Yusuke, Ishibashi, Yutaka, Ishida, Tatsuro, Fujii, Hisako, Harada-Shiba, Mariko, Kabata, Daijiro, Kihara, Yasuki, Kotani, Kazuhiko, Kurisu, Satoshi, Masuda, Daisaku, Matoba, Tetsuya, Matsuki, Kota, Mori, Kenta, Nakazato, Masamitsu, Taniuchi, Satsuki, Ueno, Hiroaki, Yamashita, Shizuya, Yoshida, Hiroshi, Yoshida, Hisako, Shoji, Tetsuo   +22 more
openaire   +2 more sources

Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial

Journal of Lipid Research, 2010
Cholesterol homeostasis, defined as the balance between absorption and synthesis, influences circulating cholesterol concentrations and subsequent coronary heart disease (CHD) risk.
Nirupa R. Matthan, Nancy Resteghini, Michele Robertson, Ian Ford, James Shepherd, Chris Packard, Brendan M. Buckley, J. Wouter Jukema, Alice H. Lichtenstein, Ernst J. Schaefer   +9 more
doaj   +1 more source

Differential gene expression of Caenorhabditis elegans grown on unmethylated sterols or 4α-methylsterols

Journal of Lipid Research, 2007
Transcriptional profiles of Caenorhabditis elegans grown on unmethylated sterols (desMSs) or on 4α-methylsterols (4MSs) were compared using microarrays.
Merris Mark, Wang Tongsheng, Soteropoulos Patricia, Lenard John   +3 more
doaj   +1 more source

Low-fat nondairy minidrink containing plant stanol ester effectively reduces LDL cholesterol in subjects with mild to moderate hypercholesterolemia as part of a Western diet [PDF]

, 2013
Peer ...
Gylling, Helena, Hallikainen, Maarit, Olsson, Johan   +2 more
core   +2 more sources

Anagliptin decreases serum lathosterol level in patients with type 2 diabetes: a pilot study [PDF]

Expert Opinion on Pharmacotherapy, 2015
The mechanism responsible for the lipid-lowering effect of dipeptidyl peptidase-4 (DPP-4) inhibitors remains unknown in humans. We evaluated the effect of anagliptin on serum lipid profiles, including cholesterol synthesis and absorption markers, in Japanese patients with type 2 diabetes.Thirty patients with type 2 diabetes (20 - 70 years old, low ...
Kazutaka, Aoki, Takahiro, Ijima, Hiroshi, Kamiyama, Kazunari, Kamiko, Yasuo, Terauchi   +4 more
openaire   +2 more sources

The Plasma Distribution of Non-cholesterol Sterol Precursors and Products of Cholesterol Synthesis and Phytosterols Depend on HDL Concentration

Frontiers in Nutrition, 2022
Non-cholesterol sterols are transported in plasma lipoproteins and are consequently important in cholesterol metabolism. We investigated the distribution of non-cholesterol sterol precursors of cholesterol synthesis (NCSPCS), oxysterols, and phytosterols
Valéria Sutti Nunes, Eliton Juniro da Silva, Guilherme da Silva Ferreira, Sayonara Ivana Santos de Assis, Patrícia Miralda Cazita, Edna Regina Nakandakare, Vanessa Helena de Souza Zago, Eliana Cotta de Faria, Eder Carlos Rocha Quintão   +8 more
doaj   +1 more source

Low density lipoprotein cholesterol is inversely correlated with abdominal visceral fat area: a magnetic resonance imaging study [PDF]

, 2011
Background Visceral Fat Area (VFA) is an independent predictor of coronary disease. While low density lipoprotein cholesterol (LDL-C) is used to determine risk and guide therapy, its accuracy fails in obese patients who may have low LDL-C despite high ...
Michel R Hoenig, Gary Cowin, Raymond Buckley, Christine McHenery, Alan Coulthard   +4 more
core   +1 more source

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

Journal of Lipid Research, 2004
The roles of polymorphisms of the sitosterolemia genes ABCG5 and ABCG8 in the regulation of cholesterol metabolism and insulin sensitivity were studied in mildly hypercholesterolemic noncoronary subjects (n = 263, 144 men and 119 women) divided into ...
Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Jyrki Ågren, Markku Laakso, Radhakrishnan A. Rajaratnam, Rainer Rauramaa, Tatu A. Miettinen   +7 more
doaj   +1 more source