Results 51 to 60 of about 10,676,082 (292)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Bridging Microdosimetry and Macrodosimetry: A Comparative Review of Computational Approaches [PDF]
Microdosimetry does not simply refer to dosimetry with small targets, but rather to dosimetry that accounts for the stochastic nature of energy deposition.
Tatsuhiko Sato
doaj +1 more source
DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation
The superior dose distribution of particle radiation compared to photon radiation makes it a promising therapy for the treatment of tumors. However, the cellular responses to particle therapy and especially the DNA damage response (DDR) is not well ...
Gerarda van de Kamp +8 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Vatis update: new and renewable energy [PDF]
Highlights - Solar-powered equipment on toll highway - Variable rotor wind turbine - Stationary fuel cell generator - Linear system to capture wave energy - Energy recovery and utilization system - RDF-fired ...
Asian and Pacific Centre for Transfer of Technology (APCTT) +2 more
core +1 more source
Heavy-ion beam, a type of ionizing radiation, has been applied to plant breeding as a powerful mutagen and is a promising tool to induce large deletions and chromosomal rearrangements. The effectiveness of heavy-ion irradiation can be explained by linear
Kotaro Ishii +13 more
doaj +1 more source
Research on Prediction Method for Heavy Ion SEE Cross-section Based on Proton SEE Cross-section
With the development of space technology and semiconductor technology, more and more microelectronic devices are used in spacecraft. Heavy ions and protons are two main particles that cause single event effect (SEE) in devices.
MA Xu;HAN Jinhua;GUO Gang;CHEN Qiming;LIU Jiancheng;ZHAO Shuyong;ZHANG Zheng
doaj
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Optimal dephasing for ballistic energy transfer in disordered linear chains
16 pages, inlcuding 9 ...
Zhang, Yang +3 more
openaire +5 more sources

