Results 61 to 70 of about 2,488,943 (332)

Current Insights into the Radiobiology of Boron Neutron Capture Therapy and the Potential for Further Improving Biological Effectiveness

Cells
Photon (X-ray) radiotherapy is the most common treatment used in cancer therapy. However, the exposure of normal tissues and organs at risk to ionising radiation often results in a significant incidence of low-grade adverse side effects, whilst high ...
Leah D. Punshon, Maria Rita Fabbrizi, Ben Phoenix, Stuart Green, Jason L. Parsons   +4 more
doaj   +1 more source

High Single-Event Burnout Resistance 4H-SiC Junction Barrier Schottky Diode

IEEE Journal of the Electron Devices Society, 2021
This paper presents a single-event burnout (SEB) resistance method for 4H-SiC Junction Barrier Schottky Diode (JBS) under high bias voltage and linear energy transfer (LET) conditions.
Mao-Bin Li, Fei Cao, Hai-Fan Hu, Xing-Ji Li, Jian-Qun Yang, Ying Wang   +5 more
doaj   +1 more source

Universal statistics of non-linear energy transfer in turbulent models

, 1996
A class of shell models for turbulent energy transfer at varying the inter-shell separation, $\lambda$, is investigated. Intermittent corrections in the continuous limit of infinitely close shells ($\lambda \rightarrow 1$) have been measured.
B. Dubrulle, C. Meneveau, D. Pisarenko, E. A. Novikov, E. B. Gledzer, E. Trovatore, G. Stolovitzky, L. Biferale, L. Biferale, L. Biferale, L. Kadanoff, L. Kadanoff, M. H. Jensen, M. Yamada, R. Benzi, R. Benzi, R. Benzi, R. Benzi, R. Benzi, R. Benzi, R. Benzi, R. Grauer, Z. S. She, Z. S. She, Z. S. She   +24 more
core   +1 more source

Hindered Coulomb explosion of embedded Na clusters -- stopping, shape dynamics and energy transport [PDF]

, 2007
We investigate the dynamical evolution of a Na$_8$ cluster embedded in Ar matrices of various sizes from N=30 to 1048. The system is excited by an intense short laser pulse leading to high ionization stages.
Ahmadi, Andrae, Andrae, Bargheer, Brack, Calvayrac, Calvayrac, Dick, Diederich, Dubertret, Duplàe, Döppner, E. Suraud, F. Fehrer, Fehrer, Fehrer, Fehrer, Gervais, Gervais, Giglio, Gresh, Gross, Harbich, Heer, Häkkinen, Legrand, Loewen, M. Bär, Mayer, Moseler, Nasluzov, Niv, Ntamack, Näher, P. M. Dinh, P.-G. Reinhard, Reinhard, Reinhard, Rhouma, Schmitt, Sieber   +40 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses

Frontiers in Pharmacology, 2017
Background and Purpose: Radiotherapy is an essential tool for cancer treatment. In order to spare normal tissues and to reduce the risk of normal tissue complications, particle therapy is a method of choice.
Bjorn Baselet, Bjorn Baselet, Omid Azimzadeh, Nadine Erbeldinger, Nadine Erbeldinger, Mayur V. Bakshi, Till Dettmering, Ann Janssen, Svetlana Ktitareva, Donna J. Lowe, Arlette Michaux, Roel Quintens, Kenneth Raj, Marco Durante, Marco Durante, Claudia Fournier, Mohammed A. Benotmane, Sarah Baatout, Sarah Baatout, Pierre Sonveaux, Soile Tapio, An Aerts   +21 more
doaj   +1 more source

DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation

Frontiers in Genetics, 2021
The superior dose distribution of particle radiation compared to photon radiation makes it a promising therapy for the treatment of tumors. However, the cellular responses to particle therapy and especially the DNA damage response (DDR) is not well ...
Gerarda van de Kamp, Gerarda van de Kamp, Tim Heemskerk, Tim Heemskerk, Roland Kanaar, Roland Kanaar, Jeroen Essers, Jeroen Essers, Jeroen Essers   +8 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Repair Kinetics of DNA Double Strand Breaks Induced by Simulated Space Radiation

Life, 2020
Radiation is unavoidable in space. Energetic particles in space radiation are reported to induce cluster DNA damage that is difficult to repair. In this study, normal human fibroblasts were irradiated with components of space radiation such as proton ...
Takashi Oizumi, Rieko Ohno, Souichiro Yamabe, Tomoo Funayama, Asako J. Nakamura   +4 more
doaj   +1 more source

High linear energy transfer carbon-ion irradiation increases the release of the immune mediator high mobility group box 1 from human cancer cells

Journal of Radiation Research, 2018
Anti-tumor immunity modulates the local effects of radiation therapy. High mobility group box 1 (HMGB1) plays a pivotal role in activating antigen-specific T-cell responses.
M. Onishi, N. Okonogi, T. Oike, Y. Yoshimoto, Hiro Sato, Yoshiyuki Suzuki, T. Kamada, T. Nakano   +7 more
semanticscholar   +1 more source