Results 231 to 240 of about 26,671 (292)

Acoustofluidic Patterning for Improved Microtissue Histology

Advanced NanoBiomed Research, EarlyView.
Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh, Emilie Vuille‐dit‐Bille, Saumitra Joshi, Nicola Gerber, Christine Fux, Annina Eichenberger, Epifania Bono, Markus Rimann, Sarah Heub, Daniel Migliozzi, Stephanie Boder‐Pasche, Gilles Weder, Jurg Dual, Mark W. Tibbitt   +13 more
wiley   +1 more source

A Novel Acetylcholine Nanosensor for Single Vesicle Storage and Sub‐Quantal Exocytosis in Living Neurons and Organoids

Angewandte Chemie, EarlyView.
Schematic representation of M@E@CF nanosensors for detecting vesicular storage and release in cholinergic neurons and brain organoids. (A) Nano‐tip microelectrodes modification via molds fabricated through 3D printing. (B) the reaction mechanism for acetylcholine detection at the electrode interface.
Wanying Zhu, Yufan Zhang, Hanwen Yu, Da Wang, Xinyue Zhang, Xiaowen Du, Shanshan Wu, Bingzhi Li, Yizhou Zhang, Hongliang Xin, Xing Guo, Yan Liu   +11 more
wiley   +2 more sources

Development and Transformation of Veterinary Experimental In Vitro Models: From 2D Culture to 3D Organoids. [PDF]

Animals (Basel)
Hu X, Xie Y, Wang J, Zhang X, Wu R.
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Fast‐Track to Functional Neurons: Accessible and Minimalistic Neurogenin 2 Programming of Human iPSCs

Advanced NanoBiomed Research, EarlyView.
Fast‐track to functional human induced pluripotent stem cell (hiPSC)‐derived neurons: This colony‐initiated differentiation approach induces neurogenin 2 overexpression in dense hiPSC colonies (day 0), resulting in a structural reorganization of the colonies (day 2) before they are replated as single cells.
Jann Harberts, Malte Siegmund, Emma Wollesen, Caroline Viola, Kim Krieg, Ole Pless, Roey Elnathan, Robert Zierold, Robert H. Blick, Nicolas H. Voelcker   +9 more
wiley   +1 more source

Mastering Organoid Growth: A Complete Guide to Overcoming Methodological Challenges. [PDF]

MedComm (2020)
Jiao C, Karakaya OF, Dadgar N, Wehrle CJ, Massoud Z, Hong H, Fairchild RL, Leipzig N, Aucejo F, Ma WW, Melenhorst JJ, Gonzales SF, Schlegel A.   +12 more
europepmc   +1 more source

Organoids in drug development: from predictive models to regulatory integration. [PDF]

Drug Discov Today
Song X, Chen X, Chen Q, Wang H, Zhang T, Liao MZ, Liu C, Yu H, Hao Y, Gu G, Cheng Z, Zhu Z, Zhang Y, Hourigan SK.   +13 more
europepmc   +1 more source

Innovations in liver organoids: the role of 3D bioprinting in creating functional organoids

Hepatobiliary Surgery and Nutrition
Zhang, Kai, Yang, Huayu
openaire   +2 more sources

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, EarlyView.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source