Results 231 to 240 of about 25,342 (266)

Toward clone‐on‐a‐chip: Ethical and legal considerations for organ‐on‐a‐chip evolution

BMEMat, EarlyView.
The term “clone‐on‐a‐chip (CoC)” is introduced as a conceptual warning for personalized organ‐on‐a‐chip platforms and not to suggest technological feasibility, where a CoC ethical discussion extends beyond issues arising from the requirements for informed consent, property rights, commercialization efforts, and cell sourcing to include potentially ...
Muhammed Erkan Karabekmez, Aliakbar Ebrahimi, Hamed Ghorbanpoor, Nicole Bassous, Su Ryon Shin, Yu Shrike Zhang, Huseyin Avci   +6 more
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Development of an alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell-derived liver organoids. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Feng Z, Zhou B, Shuai Q, Wei Y, Jin N, Wang X, Zhao H, Liu Z, Xu J, Mu J, Xie J.   +10 more
europepmc   +1 more source

Generation of Multicellular 3D Liver Organoids From Induced Pluripotent Stem Cells as a Tool for Modelling Liver Diseases. [PDF]

Bio Protoc
Maepa SW, Marakalala MJ, Ndlovu H.
europepmc   +1 more source

Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting. [PDF]

Lab Chip
Shrestha S, Lekkala VKR, Acharya P, Kang SY, Vanga MG, Lee MY.   +5 more
europepmc   +1 more source

A High-Throughput Microphysiological Liver Chip System to Model Drug-Induced Liver Injury Using Human Liver Organoids. [PDF]

Gastro Hep Adv
Meyer SR, Zhang CJ, Garcia MA, Procario MC, Yoo S, Jolly AL, Kim S, Kim J, Baek K, Kersten RD, Fontana RJ, Sexton JZ.   +11 more
europepmc   +1 more source

Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Ardisasmita AI, Joore IP, Levy N, Myszczyszyn A, Marsee A, Sinnige T, Ruiter J, Ferdinandusse S, Dudaryeva O, Gruber E, Daive V, Levato R, Spee B, Verstegen M, van der Laan L, Nieuwenhuis EES, Schene IF, Fuchs SA.   +17 more
europepmc   +1 more source

Biomaterials for the Construction of Functional Liver Organoids

Tegshjargal Badamjav, Riao Dao, Yundendash Dashzeveg, Bayar Hexig   +3 more
openaire   +1 more source

Organoids to model liver disease [PDF]

JHEP Reports, 2021
The organoid model represents a major breakthrough in cell biology that has revolutionised biomedical research. Organoids are 3D physiological in vitro structures that recapitulate morphological and functional features of in vivo tissues and offer significant advantages over traditional cell culture methods.
Sandro Nuciforo, Markus H Heim
exaly   +5 more sources

Liver Organoids, Novel and Promising Modalities for Exploring and Repairing Liver Injury

Stem Cell Reviews and Reports, 2022
The past decades have witnessed great advances in organoid technology. Liver is the biggest solid organ, performing multifaceted physiological functions. Nowadays, liver organoids have been applied in many fields including pharmaceutical research, precision medicine and disease models. Compared to traditional 2-dimensional cell line cultures and animal
Modan Yang, Xiao Xu
exaly   +5 more sources