Results 11 to 20 of about 11,072 (207)

Peptide lipidation in lysophospholipid micelles and lysophospholipid-enriched membranes

open access: yesFaraday Discussions, 2021
Acyl transfer to a membrane-associated peptide from both lysolipids and lipids occurs readily, leading to the generation of a lipidated peptide that adopts secondary structure in the absence of lipids.
Vian S. Ismail   +3 more
openaire   +6 more sources

Synthesis of Lysophospholipids [PDF]

open access: yesMolecules, 2010
New synthetic methods for the preparation of biologically active phospholipids and lysophospholipids (LPLs) are very important in solving problems of membrane–chemistry and biochemistry. Traditionally considered just as second-messenger molecules regulating intracellular signalling pathways, LPLs have recently shown to be involved in many physiological
D'ARRIGO, PAOLA, SERVI, STEFANO
openaire   +4 more sources

Preserved and variable spatial‐chemical changes of lipids across tomato leaves in response to central vein wounding reveals potential origin of linolenic acid in signal transduction cascade

open access: yesPlant-Environment Interactions, 2021
Membrane lipids serve as substrates for the generation of numerous signaling lipids when plants are exposed to environmental stresses, and jasmonic acid, an oxidized product of 18‐carbon unsaturated fatty acids (e.g., linolenic acid), has been recognized
Dušan Veličković   +13 more
doaj   +1 more source

Substrate-Specific Inhibition Constants for Phospholipase A2 Acting on Unique Phospholipid Substrates in Mixed Micelles and Membranes Using Lipidomics. [PDF]

open access: yes, 2019
Assaying lipolytic enzymes is extremely challenging because they act on water-insoluble lipid substrates, which are normally components of micelles, vesicles, and cellular membranes.
Armando, Aaron   +2 more
core   +6 more sources

Animal performance and carcass characteristics from confined lambs fed on concentrate feed and additives

open access: yesAnais da Academia Brasileira de Ciências, 2015
The number of sheep flocks in Brazil is increasing. It is known that lambs must be slaughtered when young for producing quality meat. The current study evaluated the inclusion of protected methionine, protected lysine, lysophospholipid and amylolytic ...
Tayrone F. Prado   +6 more
doaj   +1 more source

A Review of Cyclic Phosphatidic Acid and Other Potential Therapeutic Targets for Treating Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually breaks down.
Tamotsu Tsukahara   +2 more
doaj   +1 more source

Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles

open access: yesMolecules, 2022
Phospholipase A1 (PLA1) is an enzyme that cleaves an ester bond at the sn-1 position of glycerophospholipids, producing a free fatty acid and a lysophospholipid.
Shun Yaginuma   +2 more
doaj   +1 more source

Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery [PDF]

open access: yes, 2010
<b>BACKGROUND AND PURPOSE</b> Anandamide and sphingosine-1-phosphate (S1P) both regulate vascular tone in a variety of vessels. This study aimed to examine the mechanisms involved in the regulation of coronary vascular tone by anandamide and ...
Alemany   +47 more
core   +2 more sources

Group 1B phospholipase A2 deficiency protects against diet-induced hyperlipidemia in mice

open access: yesJournal of Lipid Research, 2011
Excessive absorption of products of dietary fat digestion leads to type 2 diabetes and other obesity-related disorders. Mice deficient in the group 1B phospholipase A2 (Pla2g1b), a gut digestive enzyme, are protected against diet-induced obesity and type
Norris I. Hollie, David Y. Hui
doaj   +1 more source

Sphingosine 1-phosphate receptors: do they have a therapeutic potential in cardiac fibrosis? [PDF]

open access: yes, 2017
Sphingosine 1-phosphate (S1P) is a bioactive lipid that is characterized by a peculiar mechanism of action. In fact, S1P, which is produced inside the cell, can act as an intracellular mediator, whereas after its export outside the cell, it can act as ...
Frati, Alessia   +4 more
core   +2 more sources

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