The first international symposium on lysosomes [1] was held in 1963 at the Ciba Foundation, under the chairmanship of Danielli and with the participation of a prestigious membership. It is interesting to compare our present understanding of the properties and functions of lysosomes with what was known 20 years ago.
De Duve, Christian
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Atrial Fibrillation: unravelling the significance of lysosomes in atria under normal and pathological conditions [PDF]
Lysosomes are responsible for the degradation of intracellular and extracellular macromolecules. They also play roles in signalling relevant to cardiac function and cardiac disease, however, the extent of altered lysosomal function in Atrial fibrillation
Ayagama, Rasanjini Thamali Pranitha
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The Biogenesis of Lysosomes and Lysosome-Related Organelles [PDF]
Lysosomes were once considered the end point of endocytosis, simply used for macromolecule degradation. They are now recognized to be dynamic organelles, able to fuse with a variety of targets and to be re-formed after fusion events. They are also now known to be the site of nutrient sensing and signaling to the cell nucleus. In addition, lysosomes are
J Paul, Luzio +3 more
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“LRRK2: Autophagy and Lysosomal Activity”
It has been 15 years since the Leucine-rich repeat kinase 2 (LRRK2) gene was identified as the most common genetic cause for Parkinson’s disease (PD). The two most common mutations are the LRRK2-G2019S, located in the kinase domain, and the LRRK2-R1441C,
Marta Madureira +3 more
doaj +1 more source
Cuproproteins of Hepatocyte Lysosomes in Normal and Fatty Liver [PDF]
1993-03The pathophysiological significance of cuproproteins in hepatocyte lysosomes was studied in 7 patients with structurally normal livers and 13 patients with fatty livers by energy-dispersion X-ray microanalysis.
SAKAMOTO, NOBUO +4 more
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Granular Cell Transformation in Plexiform Ameloblastoma: Case Report and Literature Review [PDF]
Ameloblastoma is the most common odontogenic tumor, primarily occurring in the posterior mandible. It is a slow-growing yet locally invasive epithelial tumor that generally follows a benign course.
Aravindan S +5 more
doaj +1 more source
A Ratiometric Fluorescent Probe for Hypochlorite and Lipid Droplets to Monitor Oxidative Stress
Mitochondria are valuable subcellular organelles and play crucial roles in redox signaling in living cells. Substantial evidence proved that mitochondria are one of the critical sources of reactive oxygen species (ROS), and overproduction of ROS ...
Mousumi Baruah +4 more
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LYSOSOME-DEPENDENT CELL DEATH DEFINES SPECIFIC ENDOTHELIAL TOXICITY OF CALCIUM PHOSPHATE BIONS
Aim of the study was to identify the mechanism of specific endothelial toxicity related to calcium phosphate bions (CPB). Material and methods. CPB and magnesium phosphate bions (MPB) were artificially synthesised through supersaturation of culture ...
D. K. Shishkova +7 more
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Lysosome Transport as a Function of Lysosome Diameter
Lysosomes are membrane-bound organelles responsible for the transport and degradation of intracellular and extracellular cargo. The intracellular motion of lysosomes is both diffusive and active, mediated by motor proteins moving lysosomes along microtubules. We sought to determine how lysosome diameter influences lysosome transport.
Debjyoti Bandyopadhyay +4 more
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Biogenesis of lysosomes in macrophages : intracellular pathway of lysosomal membrane protein to lysosomes [PDF]
Includes abstract. Includes bibliographical references (leaves 212-248)
Ebrahim, Roshan
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