Results 231 to 240 of about 26,139 (253)

RNA m6A methylation regulators in sepsis

Molecular and Cellular Biochemistry, 2023
N6-methyladenosine (m6A) modification is a class of epitope modifications that has received significant attention in recent years, particularly in relation to its role in various diseases, including sepsis. Epigenetic research has increasingly focused on m6A modifications, which is influenced by the dynamic regulation of three protein types: ‟Writers" (
Lin, Zhu   +3 more
openaire   +2 more sources

Role of m6A methylation in retinal diseases

Experimental Eye Research, 2023
Retinal diseases remain among the leading causes of visual impairment in developed countries, despite great efforts in prevention and early intervention. Due to the limited efficacy of current retinal therapies, novel therapeutic methods are urgently required. Over the past two decades, advances in next-generation sequencing technology have facilitated
Xinyu Zhu   +3 more
openaire   +2 more sources

Relative Quantification of Residue-Specific m6A RNA Methylation Using m6A-RT-QPCR

2021
Technological advances in high-throughput sequencing in combination with antibody enrichment and/or induced nucleotide-specific chemical modifications have accelerated the mapping of epitranscriptomic modifications. However, site-specific detection and quantification of m6A are still technically challenging.
Ane, Olazagoitia-Garmendia   +1 more
openaire   +2 more sources

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