Results 231 to 240 of about 836,621 (308)
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng +5 more
wiley +1 more source
METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3. [PDF]
Kaohsiung J Med SciLi R, Wang X, Du W, Li Q, Cui HP.
europepmc +1 more source
Molecular Oncology, Volume 20, Issue 10, Page 2410-2423, October 2026.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The Role of m6A Modification in the Development of Systemic Lupus Erythematosus via the TGF-β Signaling Pathway. [PDF]
J Immunol ResXia X, Qu R.
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
m6A modification on ncRNAs and underlying mechanisms of exercise in the regulation of pathological cardiac remodeling. [PDF]
Eur J Med ResYin G, He X, Chen N.
europepmc +1 more source
Advanced Science, Volume 13, Issue 56, 9 October 2026.This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng +13 more
wiley +1 more source
Research progress on the characteristics and functions of m6A modification in lung cancer tumor stem cells. [PDF]
Am J Cancer ResJiang G +5 more
europepmc +1 more source
Advanced Science, Volume 13, Issue 59, 23 October 2026.RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li +16 more
wiley +1 more source
Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication. [PDF]
Virol JNi M, Li B, Wang L, Ma S, Ma K.
europepmc +1 more source