Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation [PDF]
Mucosal-associated invariant T (MAIT) cells are innate-like T lymphocytes known to elicit potent immunity to a broad range of bacteria, mainly via the rapid production of inflammatory cytokines. Whether MAIT cells contribute to antiviral immunity is less
Corbett, Alexandra J. +13 more
core +2 more sources
4MOST low resolution spectrograph MAIT
4MOST, the 4m Multi Object Spectroscopic Telescope, is an upcoming optical, fibre-fed, MOS facility for the VISTA telescope at ESO's Paranal Observatory in Chile. Its main science drivers are in the fields of galactic archeology, high- energy physics, galaxy evolution and cosmology.
Laurent, Florence +10 more
openaire +2 more sources
When it’s good to have MAITs [PDF]
This article discusses mucosal-associated invariant T-cell prophylactic and therapeutic vaccination schemes tested by Sakai et al. in mouse models of Mycobacterium tuberculosis infection together with the outcomes and observations.
Souter, MNT, McCluskey, J, Corbett, AJ
openaire +3 more sources
Mucosal-associated invariant T (MAIT) cells are innate-like T cells which are important in the defense against certain bacteria and yeast. The reconstitution of MAIT cells after allogeneic hematopoietic stem cell transplantation (HSCT) is not known.
Martin Solders +8 more
doaj +1 more source
Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]
Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F. +3 more
core +1 more source
Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis [PDF]
__Background & Aims:__ Mucosal-associated invariant T (MAIT) cells are important innate T cells with antimicrobial and immunoregulatory activity, recently found to be depleted in blood of patients with HIV and HCV mono-infections.
Arends, J.E. (Joop) +8 more
core +1 more source
Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection. [PDF]
Mucosa-associated invariant T (MAIT) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses. Here we investigate the response of MAIT cells during acute HIV-1 infection utilizing the RV217 cohort with paired ...
Ananworanich, Jintanat +23 more
core
Mucosa-associated invariant T cells are systemically depleted in simian immunodeficiency virus-infected rhesus macaques [PDF]
Mucosa-associated invariant T (MAIT) cells contribute to host immune protection against a wide range of potential pathogens via the recognition of bacterial metabolites presented by the major histocompatibility complex class I-related molecule MR1 ...
Brenchley, Jason M. +8 more
core +1 more source
Objective: To investigate the frequency, phenotype, function, and longitudinal repertoire of mucosal-associated invariant T (MAIT) cells in relapsing remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS) patients.Methods ...
Edgar Carnero Contentti +3 more
doaj +1 more source
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells [PDF]
The major-histocompatibility-complex-(MHC)-class-I-related molecule MR1 can present activating and non-activating vitamin-B-based ligands to mucosal-associated invariant T cells (MAIT cells). Whether MR1 binds other ligands is unknown. Here we identified
A Kurioka +67 more
core +2 more sources

