Results 31 to 40 of about 10,390 (221)
Frontiers in Microbiology, 2020 Recent research has demonstrated that MAIT cells are activated by individual bacterial or yeasts species that possess the riboflavin biosynthesis pathway.
Jannike L. Krause +10 more
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Frontiers in Immunology, 2022 MAIT cells are persistently depleted and functionally exhausted in HIV-1-infected patients despite long-term combination antiretroviral therapy (cART). IL-7 treatment supports MAIT cell reconstitution in vivo HIV-1-infected individuals and rescues their ...
Fei Han +30 more
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The role of mucosal-associated invariant T cells in visceral leishmaniasis
Frontiers in Immunology, 2022 Mucosal-associated invariant T (MAIT) cells are restricted by MR1 and are known to protect against bacterial and viral infections. Our understanding of the role of MAIT cells in parasitic infections, such as visceral leishmaniasis (VL) caused by ...
Marcela de Lima Moreira +24 more
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A Role for MAIT Cells in Colorectal Cancer [PDF]
Frontiers in Immunology, 2020 MAIT cells are MR1-restricted T cells that are well-known for their anti-microbial properties, but they have recently been associated with different forms of cancer. Several studies have reported activated MAIT cells within the microenvironment of colorectal tumors, but there is conjecture about the nature of their response and whether they are ...
Stuart P. Berzins +8 more
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Frontiers in Immunology, 2017 Mucosal-associated invariant T (MAIT) cells are innate-like T cells which are important in the defense against certain bacteria and yeast. The reconstitution of MAIT cells after allogeneic hematopoietic stem cell transplantation (HSCT) is not known.
Martin Solders +8 more
doaj +1 more source
Frontiers in Immunology, 2019 Objective: To investigate the frequency, phenotype, function, and longitudinal repertoire of mucosal-associated invariant T (MAIT) cells in relapsing remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS) patients.Methods ...
Edgar Carnero Contentti +3 more
doaj +1 more source
Frontiers in Immunology, 2019 Oesophageal adenocarcinoma (OAC) is an aggressive malignancy with poor prognosis, and incidence is increasing rapidly in the Western world. Mucosal-associated invariant T (MAIT) cells recognize bacterial metabolites and kill infected cells, yet their ...
Ashanty M. Melo +20 more
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When it’s good to have MAITs [PDF]
Immunology & Cell Biology, 2020 This article discusses mucosal-associated invariant T-cell prophylactic and therapeutic vaccination schemes tested by Sakai et al. in mouse models of Mycobacterium tuberculosis infection together with the outcomes and observations.
Souter, MNT, McCluskey, J, Corbett, AJ
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Frontiers in Pharmacology, 2022 Background: Necrotizing enterocolitis (NEC) is a potentially fatal inflammatory gastrointestinal disease in preterm infants with unknown pathogenesis. Mucosal-associated invariant T (MAIT) cells primarily accumulate at sites where exposure to microbes is
Jiayi Tian +9 more
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MAIT cells in liver inflammation and fibrosis
Seminars in Immunopathology, 2022 AbstractMucosal-associated invariant T cells or MAIT cells are an abundant cell type in humans and especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge between innate and adaptive immunity, so-called innate-like or “unconventional” T cells.
Mehta, H +3 more
openaire +2 more sources