Results 21 to 30 of about 12,732 (162)

Chapare mammarenavirus - a new deadly virus outbreak: a review

International Journal of Research in Medical Sciences, 2020
In 2003 an emerging mammarenavirus (formerly arenaviruses) was discovered in Bolivia and named Chapare (CHAPV). It was related to severe and fatal haemorrhagic fever, being similar in clinical features to Machupo (MACV). In mid-2019, CHAPV was the explanation for a cluster of 5 cases, two of them laboratory confirmed, three of them fatal.
Dnyaneshwari Gujar, N. Sriram Choudary, Chaitrali Joshi, Nikhitha Raigir, Shreshth Sharma, Kommuri Baji Babu, Rahul V. C. Tiwari   +6 more
openaire   +4 more sources

Aporé virus, a novel mammarenavirus (Bunyavirales: Arenaviridae) related to highly pathogenic virus from South America [PDF]

Memorias do Instituto Oswaldo Cruz, 2019
Here, we report the complete genome sequence of the Aporé virus (Bunyavirales: Arenaviridae), obtained from a wild rodent Oligoryzomys mattogrossae captured in Mato Grosso do Sul state, Brazil.
Jorlan Fernandes, Alexandro Guterres, Renata Carvalho de Oliveira, Rodrigo Jardim, Alberto Martín Rivera Dávila, Roger Hewson, Elba Regina Sampaio de Lemos   +6 more
doaj   +3 more sources

Establishment of Recombinant Trisegmented Mopeia Virus Expressing Two Reporter Genes for Screening of Mammarenavirus Inhibitors

Viruses, 2022
Highly pathogenic Arenaviruses, like the Lassa Virus (LASV), pose a serious public health threat in affected countries. Research and development of vaccines and therapeutics are urgently needed but hampered by the necessity to handle these pathogens ...
Lisa Oestereich, Stephanie Wurr, Sabrina Bockholt   +2 more
exaly   +3 more sources

Mammarenaviruses depend on endogenous fatty acid synthesis in cell culture systems [PDF]

Journal of Lipid Research
Lassa virus (LASV) and lymphocytic choriomeningitis virus (LCMV) are Old World mammarenaviruses that, like all viruses, rely on host-derived biological molecules to complete their replication cycle.
Joseph Thomas Noble, Maryam Siddique, Kingsley Bimpeh, Nathaniel Jackson, Amaani Ibrahim, Thomas Lucien McDaniel, Nathan W. Davis, Caitlin Bone Wade, Luis Martínez-Sobrido, Kelly Marie Hines, Melinda Ann Brindley   +10 more
doaj   +2 more sources

Complete Genome Sequence of a Mammarenavirus Harbored by Rodents on Hainan Island, China [PDF]

Genome Announcements, 2018
ABSTRACT Wenzhou virus (WENV) is a rodent-borne mammarenavirus that was recently found to infect humans. In this study, we sequenced and analyzed the complete genome of a genetic variant of WENV, HMU (Hainan Medical University) virus.
Zhang, You, Rao, Langyu, Lv, Gang, Zhang, Lei, Fu, Ruijia, Wang, Shanshan, Wu, Yue, Cui, Xiuji, Yin, Feifei   +8 more
openaire   +3 more sources

The Virus–Host Interplay in Junín Mammarenavirus Infection

Viruses, 2022
Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas in Argentina.
Giovanna Lucrecia Gallo, Nora López, María Eugenia Loureiro   +2 more
doaj   +4 more sources

Detection of Latino virus (Arenaviridae: Mammarenavirus) naturally infecting Calomys callidus

Acta Tropica, 2018
Mammarenavirus species are associated with a specific rodent host species, although an increasing number of virus has been associated to more than one host, suggesting that co-evolution is less robust than initially thought. There are few eco-epidemiological studies of South America mammarenaviruses in non-endemic areas of Arenavirus Hemorrhagic Fever,
Jorlan, Fernandes, Renata Carvalho, de Oliveira, Alexandro, Guterres, Débora Ferreira, Barreto-Vieira, Ana Claudia Pereira, Terças, Bernardo Rodrigues, Teixeira, Marcos Alexandre Nunes, da Silva, Gabriela Cardoso, Caldas, Janice Mery Chicarino, de Oliveira Coelho, Ortrud Monika, Barth, Paulo Sergio, D'Andrea, Cibele Rodrigues, Bonvicino, Elba Regina Sampaio, de Lemos   +12 more
openaire   +3 more sources

Mammarenavirus Z Protein Myristoylation and Oligomerization Are Not Required for Its Dose-Dependent Inhibitory Effect on vRNP Activity [PDF]

BioChem
Background/Objectives: N-Myristoyltransferase inhibitors (NMTi) represent a novel antiviral strategy against mammarenaviruses such as Lassa and Junin viruses.
Haydar Witwit, Juan C. de la Torre
doaj   +2 more sources

Burden of rodent-borne viruses in rodents and zoonotic risk in humans in Cambodia [PDF]

Microbiology Spectrum
Rodent-borne viruses, including orthohantaviruses, mammarenaviruses, and rat hepatitis virus (HEV-C), pose significant health threats to humans, causing severe diseases such as hemorrhagic fevers, respiratory illness, and hepatitis.
Julia Guillebaud, Janin Nouhin, Vibol Hul, Thavry Hoem, Oudamdaniel Yanneth, Mala Sim, Limmey Khun, Phalla Y, Leangyi Heng, Sreymom Ken, Leakhena Pum, Reaksa Lim, Channa Meng, Kimtuo Chhel, Sithun Nuon, Sreyleak Hoem, Kunthy Nguon, Malen Chan, Sowath Ly, Erik A. Karlsson, Jean-Marc Reynes, Anavaj Sakunthabhai, Philippe Dussart, Veasna Duong   +23 more
doaj   +2 more sources

A New Transferrin Receptor Aptamer Inhibits New World Hemorrhagic Fever Mammarenavirus Entry

Molecular Therapy - Nucleic Acids, 2016
Pathogenic New World hemorrhagic fever mammarenaviruses (NWM) utilize Glycoprotein 1 (GP1) to target the apical domain of the human transferrin receptor (hTfR) for facilitating cell entry. However, the conservation between their GP1s is low.
Keith E Maier, Rohit K Jangra, David K Cureton   +2 more
exaly   +3 more sources