Multifunctional noncoding regions in the mammarenavirus genome [PDF]
VirologyIwasaki M., . Multifunctional noncoding regions in the mammarenavirus genome. Virology 605, 110464 (2025); https://doi.org/10.1016/j.virol.2025.110464.Mammarenaviruses often cause long-term asymptomatic chronic infections in their natural hosts ...
Iwasaki, Masaharu
core +4 more sources
Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation of the Z matrix protein. [PDF]
PLoS PathogensSeveral Old World and New World Mammarenavirus are responsible for hemorrhagic fever in humans. These enveloped viruses have a bi-segmented ambisense RNA genome that encodes four proteins.
Xavier Carnec +7 more
doaj +2 more sources
Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia [PDF]
eLife, 2016 Southeastern Asia is a recognised hotspot for emerging infectious diseases, many of which have an animal origin. Mammarenavirus infections contribute significantly to the human disease burden in both Africa and the Americas, but little data exists for ...
Kim R Blasdell +8 more
doaj +5 more sources
Partitioning Social and Spatial Drivers of Infection Risk. [PDF]
Ecol EvolContact rates drive disease spread, yet are often oversimplified as uniform across individuals. Using data on Mastomys natalensis, we show that exposure to Morogoro virus is linked to spatial overlap with infected conspecifics, but not overall overlap, and that direct contact occurs with only a few individuals despite broad home range overlap ...
Kirkpatrick L +4 more
europepmc +2 more sources
Prolyl tRNA Synthetase Is Required for Mammarenavirus Multiplication [PDF]
VirusesSeveral mammarenaviruses (MaAv), chiefly Lassa virus (LASV) in Western Africa and Junin virus (JUNV) in the Argentinean Pampas, cause severe disease in humans and pose important public health problems in their endemic regions.
Haydar Witwit +9 more
doaj +2 more sources
Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses [PDF]
VirusesLassa fever (LF), a viral hemorrhagic fever disease with a case fatality rate that can be over 20% among hospitalized LF patients, is endemic to many West African countries.
Chukwudi A. Ofodile +10 more
doaj +2 more sources
Editorial: Mammarenaviruses: pathogenesis, transmission, and treatment [PDF]
Frontiers in MicrobiologyRicardo Martín Gómez +2 more
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Autophagy Modulation in Mammarenavirus Infection [PDF]
Journal of Immunological Sciences, 2020 Mammarenavirus genus groups viruses causing human haemorrhagic diseases, including the New World (NW) Junín virus (JUNV), and the Old World (OW) viruses Lassa (LASV), among others. The high mortality and morbidity rates associated to pathogenic mammarenaviruses, the absence of vaccines and the constant threat of new emerging species, make these viruses
Gallo, Giovanna Lucrecia +2 more
openaire +2 more sources
Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota) [PDF]
, 2023 In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended.
Abe, Junya +31 more
core +4 more sources
Multiple Mammarenaviruses Circulating in Angolan Rodents
Viruses, 2021 Rodents are a speciose group of mammals with strong zoonotic potential. Some parts of Africa are still underexplored for the occurrence of rodent-borne pathogens, despite this high potential.
Jana Těšíková +2 more
doaj +1 more source