Results 31 to 40 of about 13,001 (185)

Understanding Sabiá virus infections (Brazilian mammarenavirus)

open access: yesTravel Medicine and Infectious Disease, 2022
Only two naturally occurring human Sabiá virus (SABV) infections have been reported, and those occurred over 20 years ago.We diagnosed two new cases of SABV infection using metagenomics in patients thought to have severe yellow fever and described new features of histopathological findings.We characterized clinical manifestations, histopathology and ...
Ana Catharina Nastri   +38 more
openaire   +2 more sources

The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus

open access: yesViruses, 2021
The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to the Old World mammarenavirus group, these viruses are not able to completely suppress the innate immune ...
Hector Moreno, Stefan Kunz
doaj   +1 more source

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales [PDF]

open access: yes, 2022
In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended.
Adkins, Scott   +11 more
core   +1 more source

A Retrospective Survey of Rodent-borne Viruses in Rural Populations of Brazilian Amazon

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: The Amazon tropical rainforest has the most dense and diverse ecosystem worldwide. A few studies have addressed rodent-borne diseases as potential hazards to humans in this region.
Jorlan Fernandes   +12 more
doaj   +1 more source

Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments

open access: yesVirulence, 2021
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections and 5,000 deaths annually.
Hannah L. Murphy, Hinh Ly
doaj   +1 more source

Structure-function relationship of the mammarenavirus envelope glycoprotein [PDF]

open access: yesVirologica Sinica, 2016
Mammarenaviruses, including lethal pathogens such as Lassa virus and Junín virus, can cause severe hemorrhagic fever in humans. Entry is a key step for virus infection, which starts with binding of the envelope glycoprotein (GP) to receptors on target cells and subsequent fusion of the virus with target cell membranes.
Wei, Wang   +4 more
openaire   +2 more sources

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. [PDF]

open access: yes, 2021
Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Archives of Virology (2021) 166:3567–3579.
Adkins, Scott   +336 more
core   +5 more sources

Presentation of antigen on extracellular vesicles using transmembrane domains from viral glycoproteins for enhanced immunogenicity

open access: yesJournal of Extracellular Vesicles, Volume 11, Issue 3, March 2022., 2022
Abstract A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immune induction remains unclear.
Kai Hu   +9 more
wiley   +1 more source

Taxonomy of the family Arenaviridae and the order Bunyavirales : update 2018 [PDF]

open access: yes, 2018
In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species.
Alkhovsky, Sergey V.   +98 more
core   +7 more sources

Characteristics of CD8+ and CD4+ Tissue‐Resident Memory Lymphocytes in the Gastrointestinal Tract

open access: yesAdvanced Gut &Microbiome Research, Volume 2022, Issue 1, 2022., 2022
Tissue‐resident memory T cells (TRMs) are plentiful in the memory T cell pool and persist in barrier sites without recirculating. Increasing evidence has shown that some kinds of CD8+ TRMs and CD4+ TRMs are resident in the gastrointestinal tract (GI), playing an important role in the context of microbiota‐immune interactions, infections, maintenance of
Pan Li   +5 more
wiley   +1 more source

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