Editorial: Mammarenaviruses: pathogenesis, transmission, and treatment [PDF]
Ricardo Martín Gómez +2 more
doaj +2 more sources
Local Maintenance and Genomic Diversity of Lymphocytic Choriomeningitis Virus in Natural Populations of House Mice in the Czech Republic Over a 24-Year Period. [PDF]
ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent‐borne zoonotic virus primarily infecting house mice. The virus can be highly pathogenic, particularly in immunocompromised individuals and in congenital infections. LCMV is distributed worldwide but shows local clustering, probably due to the highly structured populations of its ...
Jezkova I +5 more
europepmc +2 more sources
The Protein Kinase Receptor Modulates the Innate Immune Response against Tacaribe Virus
The New World (NW) mammarenavirus group includes several zoonotic highly pathogenic viruses, such as Junin (JUNV) or Machupo (MACV). Contrary to the Old World mammarenavirus group, these viruses are not able to completely suppress the innate immune ...
Hector Moreno, Stefan Kunz
doaj +1 more source
A Retrospective Survey of Rodent-borne Viruses in Rural Populations of Brazilian Amazon
INTRODUCTION: The Amazon tropical rainforest has the most dense and diverse ecosystem worldwide. A few studies have addressed rodent-borne diseases as potential hazards to humans in this region.
Jorlan Fernandes +12 more
doaj +1 more source
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections and 5,000 deaths annually.
Hannah L. Murphy, Hinh Ly
doaj +1 more source
Surveillance of Zoonotic Pathogens in Small Mammals Across Forests With Different Levels of Anthropization in Eastern France. [PDF]
The emergence of infectious diseases associated with land‐use changes is well‐documented. However, the presence and dynamics of zoonotic pathogens in small mammals within European forests, whether from rural development or urban greening, remain underexplored.
Bouilloud M +14 more
europepmc +2 more sources
Structure-function relationship of the mammarenavirus envelope glycoprotein [PDF]
Mammarenaviruses, including lethal pathogens such as Lassa virus and Junín virus, can cause severe hemorrhagic fever in humans. Entry is a key step for virus infection, which starts with binding of the envelope glycoprotein (GP) to receptors on target cells and subsequent fusion of the virus with target cell membranes.
Wei, Wang +4 more
openaire +2 more sources
Understanding Sabiá virus infections (Brazilian mammarenavirus)
Only two naturally occurring human Sabiá virus (SABV) infections have been reported, and those occurred over 20 years ago.We diagnosed two new cases of SABV infection using metagenomics in patients thought to have severe yellow fever and described new features of histopathological findings.We characterized clinical manifestations, histopathology and ...
Ana Catharina Nastri +38 more
openaire +2 more sources
Abstract A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immune induction remains unclear.
Kai Hu +9 more
wiley +1 more source
Mammarenaviruses of Rodents, South Africa and Zimbabwe
We conducted a survey for group-specific indirect immunofluorescence antibody to mammarenaviruses by using Lassa fever and Mopeia virus antigens on serum specimens of 5,363 rodents of 33 species collected in South Africa and Zimbabwe during 1964–1994 ...
Antoinette A. Grobbelaar +10 more
doaj +1 more source

