Results 61 to 70 of about 13,001 (185)

A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover

open access: yesPLOS Neglected Tropical Diseases, 2020
A detailed understanding of the mechanisms underlying the capacity of a virus to break the species barrier is crucial for pathogen surveillance and control. New World (NW) mammarenaviruses constitute a diverse group of rodent-borne pathogens that includes several causative agents of severe viral hemorrhagic fever in humans.
Moreno, Hector   +7 more
openaire   +9 more sources

Type I interferon underlies severe disease associated with Junín virus infection in mice

open access: yeseLife, 2020
Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF).
Brady T Hickerson   +5 more
doaj   +1 more source

ICTV Virus Taxonomy Profile: Arenaviridae 2023 [PDF]

open access: yes, 2023
Arenaviridae is a family for ambisense RNA viruses with genomes of about 10.5 kb that infect mammals, snakes, and fish. The arenavirid genome consists of two or three single-stranded RNA segments and encodes a nucleoprotein (NP), a glycoprotein (GP) and ...
Buchmeier, Michael J   +12 more
core   +1 more source

Taxonomy of the order Bunyavirales : second update 2018 [PDF]

open access: yes, 2019
In October 2018, the order Bunyavirales was amended by inclusion of the family Arenaviridae, abolishment of three families, creation of three new families, 19 new genera, and 14 new species, and renaming of three genera and 22 species.
Adkins, Scott   +77 more
core   +4 more sources

Screening and Identification of Lujo Virus Entry Inhibitors From an Food and Drug Administration-Approved Drugs Library

open access: yesFrontiers in Microbiology, 2021
Lujo virus (LUJV) belongs to the Old World (OW) genus Mammarenavirus (family Arenaviridae). It is categorized as a biosafety level (BSL) 4 agent. Currently, there are no U.S.
Junyuan Cao   +19 more
doaj   +1 more source

Dinucleotide biases in RNA viruses that infect vertebrates or invertebrates [PDF]

open access: yes, 2023
CpG and UpA dinucleotides are under-represented in vertebrate genomes, whereas most invertebrates only show a bias against UpA. RNA viruses are thought to have evolved genomes that resemble the dinucleotide composition of their hosts, possibly to avoid ...
Cagliani, Rachele   +4 more
core   +1 more source

RIG-I and MDA5 Protect Mice From Pichinde Virus Infection by Controlling Viral Replication and Regulating Immune Responses to the Infection

open access: yesFrontiers in Immunology, 2021
RIG-I and MDA5 are major cytoplasmic innate-immune sensor proteins that recognize aberrant double-stranded RNAs generated during virus infection to activate type 1 interferon (IFN-I) and IFN-stimulated gene (ISG) expressions to control virus infection ...
Morgan Brisse   +7 more
doaj   +1 more source

Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays

open access: yesViruses, 2018
Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000⁻300,000 individuals yearly in western Africa and frequently causes lethal disease.
Yíngyún Caì   +12 more
doaj   +1 more source

Predictors of human-infective RNA virus discovery in the United States, China, and Africa, an ecological study [PDF]

open access: yes, 2022
BACKGROUND: The variation in the pathogen type as well as the spatial heterogeneity of predictors make the generality of any associations with pathogen discovery debatable.
Chase-Topping, Margo   +3 more
core   +2 more sources

Taxonomy of the order Bunyavirales: update 2019 [PDF]

open access: yes, 2019
In February 2019, following the annual taxon ratification vote, the order Bunyavirales was amended by creation of two new families, four new subfamilies, 11 new genera and 77 new species, merging of two species, and deletion of one species.
Abudurexiti, Abulikemu   +102 more
core   +10 more sources

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