Results 71 to 80 of about 13,001 (185)
The cap-snatching SFTSV endonuclease domain is an antiviral target [PDF]
, 2020 Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%-30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Amarasinghe, Gaya K +11 more
core +1 more source
Virulence, 2022 Lassa fever (LF) is a neglected tropical disease that is caused by Lassa virus (LASV), a human hemorrhagic fever-causing mammarenavirus. A notable sequela of LF is sensorineural hearing loss (SNHL) that can develop in about 33% of the patients.
Morgan Brisse +6 more
doaj +1 more source
Autophagy modulation in mammarenavirus infection [PDF]
, 2021 Mammarenavirus genus groups viruses causing human haemorrhagicdiseases, including the New World (NW) Junín virus (JUNV), and the Old World(OW) viruses Lassa (LASV), among others.
Delgui, Laura Ruth +2 more
core
Detection of Latino virus (Arenaviridae: Mammarenavirus) naturally infecting Calomys callidus
Acta Tropica, 2018 Mammarenavirus species are associated with a specific rodent host species, although an increasing number of virus has been associated to more than one host, suggesting that co-evolution is less robust than initially thought. There are few eco-epidemiological studies of South America mammarenaviruses in non-endemic areas of Arenavirus Hemorrhagic Fever,
Jorlan, Fernandes +12 more
openaire +2 more sources
Heliyon, 2021 Arenaviral infections often result lethal hemorrhagic fevers, affecting primarily in African and South American regions. To date, there is no FDA-approved licensed vaccine against arenaviruses and treatments have been limited to supportive therapy. Hence,
Kazi Faizul Azim +6 more
doaj +1 more source
Macroevolution of virulence shifts in human-infective RNA virus species [PDF]
, 2023 Study Objectives: To determine the frequency and distribution of virulence shifts across 40 viral genera that include human-infective RNA virus species using evolutionary discrete trait models. Methods: An inhouse database containing RNA-dependent RNA
Dalhuisen, Thomas
core +1 more source
Dhati Welel virus, the missing mammarenavirus of the widespread Mastomys natalensis [PDF]
Journal of Vertebrate Biology, 2020 The Natal multimammate mouse, Mastomys natalensis, occurs throughout sub-Saharan Africa. Mitochondrial phylogenetics indicate this species was fragmented during the Pleistocene, forming six matrilineage phylogroups: A-I, A-II, A-III, B-IV, B-V, B-VI with distinct ranges.
Goüy de Bellocq, J. (Joëlle) +3 more
openaire +2 more sources
Pathogens, 2020 Lassa virus (LASV) is a mammarenavirus (arenavirus) that causes zoonotic infection in humans that can lead to fatal hemorrhagic Lassa fever (LF) disease. Currently, there are no FDA-approved vaccines or therapeutics against LASV.
Wun-Ju Shieh +4 more
doaj +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Small Science, Volume 6, Issue 1, January 2026.Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Advances in Virology, Volume 2018, Issue 1, 2018., 2018 Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. In addition, this approach has also helped in establishing the associations of viromes with many diseases.
Andrey A. Ayginin +10 more
wiley +1 more source