Results 81 to 90 of about 12,650 (152)
Dynamics of Acute Infection with Mammarenavirus Wenzhouense in Rattus norvegicus
VirusesWhile Mammarenavirus Wenzhouense (WENV) is broadly distributed across Asia, the dynamics of WENV infection remain unclear. In this study, a field-derived strain of WENV was used to inoculate Sprague Dawley (SD) rats by intramuscular injection, and the process of viral infection was observed over the course of 28 d.
Shanshan Du +12 more
openaire +3 more sources
Novel Oliveros-like Clade C Mammarenaviruses from Rodents in Argentina, 1990–2020
VirusesFollowing an Argentine Hemorrhagic Fever (AHF) outbreak in the early 1990s, a rodent survey for Junín virus, a New World Clade B arenavirus, in endemic areas of Argentina was conducted.
Elizabeth Shedroff +12 more
doaj +1 more source
Potential of Viruses as Environmental Etiological Factors for Non-Syndromic Orofacial Clefts
VirusesIn this study, we analyzed the potential of viral infections in the species Homo sapiens as environmental causes of orofacial clefts (OFCs). A scoring system was adapted for qualitatively assessing the potential of viruses to cause cleft lip and/or ...
Thiago S. Messias +3 more
doaj +1 more source
Effect of the AHR Inhibitor CH223191 as an Adjunct Treatment for Mammarenavirus Infections
International Journal of Molecular SciencesThe family Arenaviridae encompasses zoonotic, rodent-borne pathogens (e.g., Lassa, Machupo, and Junín viruses) that cause severe viral hemorrhagic fevers with high case fatality rates. The current therapeutic landscape is severely limited, underscoring the urgent need for novel antiviral strategies.
Miguel Angel Pelaez +4 more
openaire +3 more sources
PLoS Pathogens, 2018 Several mammalian arenaviruses (mammarenaviruses) cause hemorrhagic fevers in humans and pose serious public health concerns in their endemic regions.
Masaharu Iwasaki +6 more
doaj +1 more source
Viruses, 2018 New World arenaviruses cause fatal hemorrhagic disease in South America. Pirital virus (PIRV), a mammarenavirus hosted by Alston’s cotton rat (Sigmodon alstoni), causes a disease in Syrian golden hamsters (Mesocricetus auratus) (biosafety level-3 ...
Corey L. Campbell +7 more
doaj +1 more source
Virology, 2018 Junín arenavirus infections are associated with high levels of interferons in both severe and fatal cases. Upon Junín virus (JUNV) infection a cell signaling cascade initiates, that ultimately attempts to limit viral replication and prevent infection progression through the expression of host antiviral proteins.
Peña Cárcamo, José Rafael +7 more
openaire +3 more sources
The ever-expanding diversity and complexity of the Arenaviridae family
Virulence, 2023 Hinh Ly
doaj +1 more source
Review of Mammarenavirus Biology and Replication
Review of Mammarenavirus Biology and ReplicationThe family Arenaviridae is divided into three genera: Mammarenavirus, Reptarenavirus, and Hartmanivirus. The Mammarenaviruses contain viruses responsible for causing human hemorrhagic fever diseases including New World viruses Junin, Machupo, Guanarito, Sabia, and Chapare virus and Old World viruses Lassa, and Lujo virus.
openaire
Dynamics of Mammarenavirus Wenzhouense Acute Infection in the Rodent Rattus norvegicus
Mammarenavirus Wenzhouense (WENV) is broadly distributed in Asia, while the he dynamics process of WENV infection remains unclear. A field derived strain of WENV was used to inoculate Sprague-Dawley (SD) rats by intramuscular injection, the process of virus infection was de-tected by controlling time for 28 days.
ShanShan Du +12 more
openaire +1 more source