Results 91 to 100 of about 19,208 (245)

Coat colour phenotype of Qingyu pig is associated with polymorphisms of melanocortin receptor 1 gene [PDF]

Asian-Australasian Journal of Animal Sciences, 2017
Objective Qingyu pig, a Chinese indigenous pig breed, exhibits two types of coat colour phenotypes, including pure black and white with black spotting respectively.
Xiaoqian Wu, Zhendong Tan, Linyuan Shen, Qiong Yang, Xiao Cheng, Kun Liao, Lin Bai, Surong Shuai, Mingzhou Li, Xuewei Li, Shunhua Zhang, Li Zhu   +11 more
doaj   +1 more source

From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe

Molecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT High‐quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample‐handling procedures leading up to nucleic acid ...
Katja Reichel, Jaakko Pohjoismäki, Jonas J. Astrin, Astrid Böhne, Chiara Bortoluzzi, Elena Bužan, Javier del Campo, Claudio Ciofi, Camilla B. Di‐Nizo, Pradeep K. Divakar, Carola Greve, Vladimír Hampl, Leon Hilgers, Veronika N. Laine, Jennifer A. Leonard, Jesus Lozano‐Fernandez, Lada Lukić Bilela, Camila J. Mazzoni, Ann M. McCartney, José Melo‐Ferreira, Rita Monteiro, Rebekah A. Oomen, Martina Pavlek, João Pimenta, Michal Rindos, Ole Seehausen, Andrii Tarieiev, Salvatore Tomasello, Olga Vinnere Pettersson, Robert M. Waterhouse, Alexandra A.‐T. Weber, Oleksandr Zinenko, Christian de Guttry   +32 more
wiley   +1 more source

Germline MC1R Variants and BRAF Mutant Melanoma [PDF]

Journal of Investigative Dermatology, 2008
Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between
Hacker, Elke, Hayward, Nicholas K.
openaire   +1 more source

Involvement of the melanocortin-1 receptor in acute pain and pain of inflammatory but not neuropathic origin.

PLoS ONE, 2010
BackgroundResponse to painful stimuli is susceptible to genetic variation. Numerous loci have been identified which contribute to this variation, one of which, MC1R, is better known as a gene involved in mammalian hair colour. MC1R is a G protein-coupled
Ada Delaney, Margaret Keighren, Susan M Fleetwood-Walker, Ian J Jackson   +3 more
doaj   +1 more source

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up [PDF]

, 2015
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci.
Bataille, V. (Veronique), Chaitanya, L.C. (Lakshmi), Duffy, D.L. (David), Glass, D. (Daniel), Henders, A.K. (Anjali), Hofman, A. (Albert), Hysi, P.G. (Pirro), IJcken, W.F.J. (Wilfred) van, Jacobs, L.C. (Leonie), Kayser, M.H. (Manfred), Lao Grueso, O. (Oscar), Liu, F. (Fan), Mangino, M. (Massimo), Martin, N.G. (Nicholas), Montgomery, G.W. (Grant), Nijsten, T.E.C. (Tamar), Palstra, R.-J.T.S. (Robert-Jan), Rivadeneira Ramirez, F. (Fernando), Spector, T.D. (Timothy), Sturm, R.A. (Richard A.), Uitterlinden, A.G. (André), Visser, M. (Mijke), Walsh, S. (Susan), Wollstein, A. (Andreas), Zhong, K. (Kaiyin), Zhu, G. (Gu)   +25 more
core   +1 more source

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

International Journal of Cosmetic Science, Volume 48, Issue 1, Page 1-15, February 2026.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin, Béatrice Le Varlet, Claire Regazzetti, Thierry Passeron, Jinhua Wang, David E. Fisher, Philippe Schaison, Braham Shroot   +7 more
wiley   +1 more source

Variability of the mc1r gene in melanic and non-melanic Podarcis lilfordi and Podarcis pityusensis from the Balearic archipelago.

PLoS ONE, 2013
The association between polymorphism at the mc1r locus and colour variation was studied in two wall lizard species (Podarcis lilfordi and P. pityusensis) from the Balearic archipelago.
Joana M Buades, Virginia Rodríguez, Bàrbara Terrasa, Valentin Pérez-Mellado, Richard P Brown, Jose A Castro, Antònia Picornell, M M Ramon   +7 more
doaj   +1 more source

Diversity across major and candidate genes in European local pig breeds [PDF]

, 2018
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds.
Alves, E., Araujo, J.P., Bozzi, R., Candek-Potokar, M., Charneca, R., Crovetti, J., Djurkin-Kusec, I., Estellé, J., Fernandéz, A.I., Fontanesi, L., Gallo, M., García, F., García-Casco, J., Geraci, C., Karolyi, D., Kusec, G., Martins, J.M., Mercat, M.J., Muñoz, M., Núñez, Y., Quintanilla, R., Radovic, C., Razmaite, V., Riquet, J., Savic, R., Skrlep, M., Tibau, J., Zimmer, C., Óvilo, C.   +28 more
core   +1 more source

Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao, Rui Luo, Ying Deng, Hongqiu Yang, Yu Du   +4 more
wiley   +1 more source

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]

, 2019
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret, Berberovic, Zorana, Clary, Dave, Eskandarian, Mohammad, Flenniken, Ann M, International Mouse Phenotyping Consortium, Lloyd, KC Kent, McKerlie, Colin, Moore, Bret A, Moshiri, Ala, Moshiri, Ata S, Murphy, Christopher J, Newbigging, Susan, Nutter, Lauryl MJ, Owen, Celeste, Thomasy, Sara M   +15 more
core