Results 41 to 50 of about 19,208 (245)
British Journal of Dermatology, 2022 Hypomorphic MC1R variants are the most prevalent genetic determinants of melanoma risk in the white population. However, the genetic background of patients with wildtype (WT) MC1R melanoma is poorly studied.
N. Calbet-Llopart +11 more
semanticscholar +1 more source
In Vitro Behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants. [PDF]
, 2019 Co-inheritance of germline mutation in cyclin-dependent kinase inhibitor 2A (CDKN2A) and loss-of-function (LOF) melanocortin 1 receptor (MC1R) variants is clinically associated with exaggerated risk for melanoma.
Abdel-Malek, ZA +10 more
core +2 more sources
Identification of two new recessive MC1R alleles in red‐coloured Evolèner cattle and other breeds
Animal Genetics, 2022 Sequence variations in the melanocortin‐1 receptor (MC1R) gene are associated with melanism in different animal species. Six functionally relevant alleles have been described in cattle to date.
Miriam Hauser +8 more
semanticscholar +1 more source
Assessing losses of genetic variability in the endangered Mallorquí horse
Czech Journal of Animal Science, 2010 Information contained in the studbook of the endangered Mallorquí horse was analysed to assess the genetic variability of the breed. Also, the effect of selection for coat colour variation was assessed using a set of 15 microsatellites genotyped on 68 ...
I. Álvarez +5 more
doaj +1 more source
Pigment Intensity in Dogs is Associated with a Copy Number Variant Upstream of KITLG. [PDF]
, 2020 Dogs exhibit a wide variety of coat color types, and many genes have been identified that control pigment production, appearance, and distribution. Some breeds, such as the Nova Scotia Duck Tolling Retriever (NSDTR), exhibit variation in pheomelanin ...
Affolter, Verena +6 more
core +2 more sources
Animals, 2021 Simple Summary Coat color is an important breed characteristic and economic trait for rabbits, and it is regulated by a few genes. In this study, the gene frequencies of some pigmentation genes were investigated in four Chinese native rabbit breeds with ...
Xianbo Jia +5 more
semanticscholar +1 more source
MC1R Variants Increase Risk of Melanomas Harboring BRAF Mutations [PDF]
Journal of Investigative Dermatology, 2008 Melanocortin-1 receptor (MC1R) variants have been associated with BRAF (v-raf murine sarcoma viral oncogene homolog B1) mutations in non-CSD (chronic solar-damaged) melanomas in an Italian and an American population. We studied an independent Italian population of 330 subjects (165 melanoma patients and 165 controls) to verify and estimate the ...
Fargnoli, Mc +16 more
openaire +7 more sources
Polymorphic loci of coat color in mini-pigs
Вавиловский журнал генетики и селекции, 2016 The present work is phenomenological and purely descriptive. It shows polymorphism of colors in a breeding group of mini-pig in the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (ICG SB RAS) and makes some ...
S. V. Nikitin +5 more
doaj +1 more source
Podarcis siculus latastei (Bedriaga, 1879) of the western pontine islands (italy) raised to the species rank, and a brief taxonomic overview of podarcis lizards [PDF]
, 2019 In recent years, great attention has been paid to many Podarcis species for which the observed intra-specific variability often revealed species complexes still characterized by an unresolved relationship. When compared to other species, P.
Bohme, W. +3 more
core +1 more source
Behind the Scene: Exploiting MC1R in Skin Cancer Risk and Prevention
Genes, 2021 Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the skin in white populations. An increased risk in the development of skin cancers has been associated with the combination of several environmental factors (i.e ...
M. Manganelli +6 more
semanticscholar +1 more source