MC1RVariation in a New Mexico Population [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2019 AbstractBackground:The Melanocortin 1 Receptor (MC1R) contributes to pigmentation, an important risk factor for developing melanoma. Evaluating SNPs in MC1R and association with race/ethnicity, skin type, and perceived cancer risk in a New Mexico (NM) population will elucidate the role of MC1R in a multicultural population.Methods:We genotyped MC1R in ...
Kirsten A.M. White +12 more
openaire +2 more sources
Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor [PDF]
Endocrinology and Metabolism, 2014 BackgroundMelanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells.
Ikjoo Seong, Jaesang Kim
doaj +1 more source
Melanism as a potential thermal benefit in eastern fox squirrels (Sciurus niger) [PDF]
, 2019 Melanistic fox squirrels (Sciurus niger) have expanded westward and increased in frequency in the Omaha, Nebraska, and Council Bluffs, Iowa, metropolitan areas.
Ciurej, Amanda K. +3 more
core +2 more sources
Differentiating Pigs from Wild Boars Based on NR6A1 and MC1R Gene Polymorphisms
Animals, 2021 Simple Summary Wild boar meat is much more expensive than pork. Therefore, there are cases when pork is added to wild boar meat products, but this information is not included on the product label.
A. Koseniuk +4 more
semanticscholar +1 more source
Molecules, 2021 Excess melanin deposition in the skin causes cosmetic problems. HSP70 upregulation decreases microphthalmia-associated transcription factor (MITF) expression, which eventually decreases tyrosinase activity and melanogenesis.
Hyoung Moon Kim +7 more
doaj +1 more source
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. [PDF]
PLoS Genetics, 2007 Genetic variation at the melanocortin 1 receptor (MC1R) is an important risk factor for developing ultraviolet (UV) radiation-induced skin cancer, the most common form of cancer in humans.
Craig S April, Gregory S Barsh
doaj +1 more source
Evolutionary and demographic correlates of Pleistocene coastline changes in the Sicilian wall lizard Podarcis wagleriana [PDF]
, 2019 Aim Emergence of coastal lowlands during Pleistocene ice ages might have provided conditions for glacial expansions (demographic and spatial), rather than contraction, of coastal populations of temperate species. Here, we tested these predictions in the
Canestrelli, Daniele +6 more
core +1 more source
The
BMC Research Notes, 2011 Background The guppy (Poecilia reticulata) is an important model organism for studying sexual selection; male guppies have complex and conspicuous pigmentation, and female guppies exhibit preferences for males with specific color spots. Understanding the
Yokoyama Jun +4 more
doaj +1 more source
International ImmunopharmacologyBACKGROUND Until 2021, colon cancer was a leading cancer globally. Early detection improves outcomes; however, advanced cases still having poor prognosis.
Shaoliang Zhu +5 more
semanticscholar +1 more source
Who's behind that mask and cape? The Asian leopard cat's Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed. [PDF]
, 2014 Coat colours and patterns are highly variable in cats and are determined mainly by several genes with Mendelian inheritance. A 2-bp deletion in agouti signalling protein (ASIP) is associated with melanism in domestic cats. Bengal cats are hybrids between
Davis, BW +5 more
core +1 more source