Results 111 to 120 of about 36,927 (297)
MDSC: posible conexión entre enfermedad periodontal y otras afecciones inflamatorias [PDF]
La enfermedad periodontal (EP) es una condición inflamatoria altamente prevalente que ha sido asociada a diferentes enfermedades. Diversos factores inmunológicos están involucrados en dicha asociación. Las células supresoras de origen mieloide (MDSC) son
Del Muro-Casas, Fátima Erendida +6 more
core +1 more source
Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer
Advanced Science, EarlyView.Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang +17 more
wiley +1 more source
Effect of G-MDSC on IFN-gamma production.
, 2014 (A) Cord blood CD3pos T cells and adult CD3pos CD45ROneg T cells were assessed for IFN-gamma production by ELISpot after anti-CD3/CD28 bead stimulation (n = 11 independent experiments performed in triplicate for neonates and 9 independent experiments for
Helen Horton (10466) +8 more
core +1 more source
Cancer Medicine, 2020 Objective Myeloid‐derived suppressor cells (MDSCs) facilitate tumor growth and development by suppressing T cell function; however, their role in acute myeloid leukemia (AML) remains unclear.
Shin Young Hyun +10 more
doaj +1 more source
Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes
Advanced Science, EarlyView.The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu +5 more
wiley +1 more source
, 2018 Nosocomial bacterial infections (NBI) and necrotizing enterocolitis (NEC) are among the main reasons for death in preterm infants. Both are often caused by bacteria coming from the infected infant’s gut and feeding with breast milk (BM) seems beneficial ...
Gerhard Brodbeck (5228978) +17 more
core +1 more source
Advanced Science, EarlyView.We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen +15 more
wiley +1 more source
Frontiers in Immunology, 2019 Myeloid-derived suppressor cells (MDSC) emerged as major factors driving the tumor progression due to numerous immunosuppressive mechanisms they possess.
Sergej Tomić +10 more
doaj +1 more source
Advanced Science, EarlyView.Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang +9 more
wiley +1 more source
MDSC increased in tumor bearing mice as a function of tumor growth.
, 2013 1A, representative FACS plots for MDSC in blood, BM, spleen and tumor of 3LL tumor bearing mice (Days 7, 14 and 21) in comparison to naive mice. 1B, FACS data for MDSC frequency in blood, BM, spleen and tumor (Days 7, 14 and 21) represented as bar graphs
Sherven Sharma (95255) +10 more
core +1 more source