Results 11 to 20 of about 48,562 (195)
Melasma Clinical Features, Diagnosis, Epidemiology and Etiology: An Update Review
Siriraj Medical Journal, 2021 Melasma is one of the commonest dermatological challenges that facing dermatologists in the whole world. Most of the previously published articles regarding melasma usually focused on its management and the newly discovered drugs; however, the ...
Mohammad Ahmad Abdalla
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Frontiers in Immunology, 2023 IntroductionPL8177 is a potent and selective agonist of the melanocortin 1 receptor (MC1R). PL8177 has shown efficacy in reversing intestinal inflammation in a cannulated rat ulcerative colitis model.
John Dodd +8 more
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Impact of the Central Histaminergic and Melanocortin Systems on Leptin-Induced Hypophagia in Neonatal Layer Chicken [PDF]
Archives of Razi Institute, 2021 The present study aimed to assess the probable impact of the central histaminergic and melanocortin systems on leptin-induced hypophagia in neonatal layer chickens.
M Shalikar +3 more
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Melanocortin 4 receptor signaling in Sim1 neurons permits sexual receptivity in female mice
Frontiers in Endocrinology, 2023 IntroductionFemale sexual dysfunction affects approximately 40% of women in the United States, yet few therapeutic options exist for these patients. The melanocortin system is a new treatment target for hypoactive sexual desire disorder (HSDD), but the ...
Erin A. Semple +9 more
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Melanocortins, Melanocortin Receptors and Multiple Sclerosis
Brain Sciences, 2017 The melanocortins and their receptors have been extensively investigated for their roles in the hypothalamo-pituitary-adrenal axis, but to a lesser extent in immune cells and in the nervous system outside the hypothalamic axis. This review discusses corticosteroid dependent and independent effects of melanocortins on the peripheral immune system ...
Robert P. Lisak, Joyce A. Benjamins
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The effect of human wharton’s jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to
Fatemeh Sabet Sarvestani +5 more
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Hypothalamic Control of Brown Adipose Tissue Thermogenesis
Frontiers in Systems Neuroscience, 2015 It has long been known, in large part from animal studies, that the control of brown adipose tissue (BAT) thermogenesis is insured by the central nervous system, which integrates several stimuli in order to control BAT activation through the sympathetic ...
Sebastien M Labbe* +5 more
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Frontiers in Marine Science, 2022 Overexpression of asip1 in transgenic zebrafish disrupts dorsoventral pigment pattern in addition to increasing food intake levels and linear growth. A higher feed intake is unnecessary in transgenic fish to enable larger and heavier growth.
Esther Leal +7 more
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Journal of Lipid Research, 2007 During our study of the reversal of seasonal obesity in Siberian hamsters, we found an interaction between receptors for the pineal hormone melatonin and the sympathetic nervous system (SNS) outflow from brain to white adipose tissue (WAT).
Timothy J. Bartness, C.K. Song
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eLife, 2016 The Melanocortin Receptor Accessory Protein 2 (MRAP2) is an important regulator of energy homeostasis and its loss causes severe obesity in rodents. MRAP2 mediates its action in part through the potentiation of the MC4R, however, it is clear that MRAP2 ...
Anna L Chaly +3 more
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