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microRNAs in the Regulation of Melanogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Melanogenesis is the process leading to the synthesis of melanin, the main substance that influences skin color and plays a pivotal role against UV damage. Altered melanogenesis is observed in several pigmentation disorders. Melanogenesis occurs in specialized cells called melanocytes, physically and functionally related by means of autocrine and ...
Giulia Di Mauro   +2 more
exaly   +4 more sources

Signaling Pathways in Melanogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Melanocytes are melanin-producing cells found in skin, hair follicles, eyes, inner ear, bones, heart and brain of humans. They arise from pluripotent neural crest cells and differentiate in response to a complex network of interacting regulatory pathways. Melanins are pigment molecules that are endogenously synthesized by melanocytes.
Graeme Finlay   +2 more
exaly   +4 more sources

Boolean model for melanogenesis

Physical Biology, 2021
Abstract Melanogenesis is a highly regulated process through which the pigment melanin is produced in skin cells. Irregularities in the molecular events that govern the process of skin pigmentation can cause disorders like vitiligo. In order to understand the biology of disease progression, it is important to have
Pooja Dnyane, Chetan Gadgil
openaire   +2 more sources

Epigenetic regulation of melanogenesis

Ageing Research Reviews, 2021
Melanogenesis is a complex process in which melanin is synthesized in melanocytes and transported to keratinocytes, which involves multiple genes and signaling pathways. Epigenetics refers to the potential genetic changes that affect gene expression without involving changes in the original sequence of DNA nucleotides.
Shihang Zhou   +12 more
openaire   +2 more sources

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