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Polianthes tuberosa L. Extract suppresses melanogenesis through concurrent Inhibition of cAMP/CREB and MAPK signaling pathways. [PDF]
Li Q +6 more
europepmc +1 more source
TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis
Sharma N +4 more
europepmc +1 more source
microRNAs in the Regulation of Melanogenesis [PDF]
Melanogenesis is the process leading to the synthesis of melanin, the main substance that influences skin color and plays a pivotal role against UV damage. Altered melanogenesis is observed in several pigmentation disorders. Melanogenesis occurs in specialized cells called melanocytes, physically and functionally related by means of autocrine and ...
Giulia Di Mauro +2 more
exaly +4 more sources
Signaling Pathways in Melanogenesis [PDF]
Melanocytes are melanin-producing cells found in skin, hair follicles, eyes, inner ear, bones, heart and brain of humans. They arise from pluripotent neural crest cells and differentiate in response to a complex network of interacting regulatory pathways. Melanins are pigment molecules that are endogenously synthesized by melanocytes.
Graeme Finlay +2 more
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Boolean model for melanogenesis
Physical Biology, 2021Abstract Melanogenesis is a highly regulated process through which the pigment melanin is produced in skin cells. Irregularities in the molecular events that govern the process of skin pigmentation can cause disorders like vitiligo. In order to understand the biology of disease progression, it is important to have
Pooja Dnyane, Chetan Gadgil
openaire +2 more sources
Epigenetic regulation of melanogenesis
Ageing Research Reviews, 2021Melanogenesis is a complex process in which melanin is synthesized in melanocytes and transported to keratinocytes, which involves multiple genes and signaling pathways. Epigenetics refers to the potential genetic changes that affect gene expression without involving changes in the original sequence of DNA nucleotides.
Shihang Zhou +12 more
openaire +2 more sources

