Results 21 to 30 of about 177,226 (339)
Membrane Cofactor Protein (MCP; CD46): Isoform-Specific Tyrosine Phosphorylation [PDF]
The Journal of Immunology, 2000 Abstract Membrane cofactor protein (MCP; CD46) is a widely expressed type 1 transmembrane glycoprotein that inhibits complement activation on host cells. It also is a receptor for several pathogens including measles virus, Streptococcus pyogenes, Neisseria gonorrhea, and Neisseria meningitidis.
G, Wang +3 more
openaire +2 more sources
The Bacterial Photosynthetic Reaction Center as a Model for Membrane Proteins [PDF]
, 1989 Membrane proteins participate in many fundamental cellular processes. Until recently, an understanding of the function and properties of membrane proteins was hampered by an absence of structural information at the atomic level.
Allen, J. P. +4 more
core +1 more source
Protective effect of membrane cofactor protein against complement-dependent injury [PDF]
Acta Pharmacologica Sinica, 2005 To evaluate the protective role of membrane cofactor protein (MCP, CD46) on complement-dependent injury.MCP was separated by ion exchange chromatography on a DEAE sephadex A-50 column from pig erythrocyte ghosts. Its protective effect was tested in models such as cobra venom factor (CVF)-induced platelet metamorphosis and aggregation, human serum ...
Dong, Xu +3 more
openaire +2 more sources
eLife, 2017 The majority of multi-spanning membrane proteins are co-translationally inserted into the bilayer by the Sec pathway. An important subset of membrane proteins have globular, cofactor-containing extracytoplasmic domains requiring the dual action of the co-
Fiona J Tooke +4 more
doaj +1 more source
Multi-heme Cytochromes in Shewanella oneidensis MR-1:Structures, functions and opportunities [PDF]
, 2015 Multi-heme cytochromes are employed by a range of microorganisms to transport electrons over distances of up to tens of nanometers. Perhaps the most spectacular utilization of these proteins is in the reduction of extracellular solid substrates ...
Brown JP +9 more
core +1 more source
Tissue factor residues that putatively interact with membrane phospholipids. [PDF]
PLoS ONE, 2014 Blood clotting is initiated by the two-subunit enzyme consisting of the plasma protease, factor VIIa (the catalytic subunit), bound to the integral membrane protein, tissue factor (the regulatory subunit).
Ke Ke, Jian Yuan, James H Morrissey
doaj +1 more source
Терапевтический архив, 2023 We report a case of atypical hemolytic uremic syndrome (aHUS) that occurred after childbirth in a patient with a history of numerous recurrent episodes of TMA with nephrotic proteinuria and impaired renal function.
Tatiana V. Kirsanova +4 more
doaj +1 more source
Characterization of the Arsenate Respiratory Reductase from Shewanella sp. Strain ANA-3 [PDF]
, 2008 Microbial arsenate respiration contributes to the mobilization of arsenic from the solid to the soluble phase in various locales worldwide. To begin to predict the extent to which As(V) respiration impacts arsenic geochemical cycling, we characterized ...
Keeffe, Jennifer R. +2 more
core +2 more sources
Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
BMC Biology, 2011 Background Ire1 is a signal transduction protein in the endoplasmic reticulum (ER) membrane that serves to adjust the protein-folding capacity of the ER according to the needs of the cell.
Stroud Robert M +7 more
doaj +1 more source
Frontiers in Genetics, 2021 Recent evidence suggests that iron-sulfur clusters (ISCs) in DNA replicative proteins sense DNA-mediated charge transfer to modulate nuclear DNA replication.
Minyoung So +8 more
doaj +1 more source