Results 21 to 30 of about 178,051 (334)

Atypical Hemolytic Uremic Syndrome Triggered by Acute Pancreatitis in a Patient with a Membrane Cofactor Protein (CD46) Genetic Variant [PDF]

Intern Med
Kosuke Mochizuki, Naohiro Toda, Masaaki Fujita, Satoshi Kurahashi, Hisako Hirashima, Kazuki Yoshioka, Tomoya Kitagawa, Ishii Akira, Toshiyuki Komiya   +8 more
openalex   +3 more sources

Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid [PDF]

PeerJ, 2013
Cell density is the critical parameter controlling tendon morphogenesis. Knowing its neighbors allows a cell to regulate correctly its proliferation and collagen production.
Christopher J. Petzold, Richard I. Schwarz   +1 more
doaj   +2 more sources

Functional properties of membrane cofactor protein of complement [PDF]

Biochemical Journal, 1989
Membrane cofactor protein (MCP or gp45-70) of the complement system is a cofactor for factor I-mediated cleavage of fluid-phase C3b and C3b-like C3, which opens the thioester bond. In the present study the activity of MCP was further characterized. Unexpectedly, in the absence of factor I, MCP stabilized the alternative- and, to a lesser extent, the ...
T, Seya, J P, Atkinson
openaire   +2 more sources

A membrane‐bound [NiFe]‐hydrogenase large subunit precursor whose C‐terminal extension is not essential for cofactor incorporation but guarantees optimal maturation

MicrobiologyOpen, 2020
[NiFe]‐hydrogenases catalyze the reversible conversion of molecular hydrogen into protons end electrons. This reaction takes place at a NiFe(CN)2(CO) cofactor located in the large subunit of the bipartite hydrogenase module. The corresponding apo‐protein
Sven Hartmann, Stefan Frielingsdorf, Giorgio Caserta, Oliver Lenz   +3 more
doaj   +1 more source

Computational Analysis of CD46 Protein Interaction with SARS-CoV-2 Structural Proteins: Elucidating a Putative Viral Entry Mechanism into Human Cells

Viruses, 2023
This study examines an unexplored aspect of SARS-CoV-2 entry into host cells, which is widely understood to occur via the viral spike (S) protein’s interaction with human ACE2-associated proteins.
Pavel Vassiliev, Evgenii Gusev, Maria Komelkova, Andrey Kochetkov, Maria Dobrynina, Alexey Sarapultsev   +5 more
doaj   +1 more source

Membrane cofactor protein (MCP; CD46) expression in transgenic mice [PDF]

Clinical and Experimental Immunology, 2001
SUMMARYHuman membrane cofactor protein (MCP; CD46) is a widely distributed complement regulator. In the mouse, expression of MCP is largely restricted to the testis while a related, widely expressed protein (Crry) appears to perform MCP's (CD46) regulatory activity.
C, Kemper, M, Leung, C B, Stephensen, C A, Pinkert, M K, Liszewski, R, Cattaneo, J P, Atkinson   +6 more
openaire   +2 more sources

Plants lacking the main light-harvesting complex retain photosystem II macro-organization [PDF]

, 2003
Photosystem II (PSII) is a key component of photosynthesis, the process of converting sunlight into the chemical energy of life. In plant cells, it forms a unique oligomeric macrostructure in membranes of the chloroplasts.
A Haldrup, A Kuttkat, A Zouni, AE Yakushevska, AV Ruban, B Hankamer, B Hankamer, DA Berthold, EJ Boekema, EJ Boekema, EJ Boekema, EJ Boekema, G Garab, GF Peter, H Paulsen, J Andersson, J Barber, J Nield, JF Allen, P Horton, R Croce, RG Walters, S Hobe, S Jansson, S Jansson, T Bibby, UK Laemmli, W Kühlbrandt   +27 more
core   +9 more sources

The Bacterial Photosynthetic Reaction Center as a Model for Membrane Proteins [PDF]

, 1989
Membrane proteins participate in many fundamental cellular processes. Until recently, an understanding of the function and properties of membrane proteins was hampered by an absence of structural information at the atomic level.
Allen, J. P., Feher, G., Komiya, H., Rees, D. C., Yeates, T. O.   +4 more
core   +1 more source

A unifying mechanism for the biogenesis of membrane proteins co-operatively integrated by the Sec and Tat pathways

eLife, 2017
The majority of multi-spanning membrane proteins are co-translationally inserted into the bilayer by the Sec pathway. An important subset of membrane proteins have globular, cofactor-containing extracytoplasmic domains requiring the dual action of the co-
Fiona J Tooke, Marion Babot, Govind Chandra, Grant Buchanan, Tracy Palmer   +4 more
doaj   +1 more source

Characterization of the Arsenate Respiratory Reductase from Shewanella sp. Strain ANA-3 [PDF]

, 2008
Microbial arsenate respiration contributes to the mobilization of arsenic from the solid to the soluble phase in various locales worldwide. To begin to predict the extent to which As(V) respiration impacts arsenic geochemical cycling, we characterized ...
Keeffe, Jennifer R., Malasarn, Davin, Newman, Dianne K.   +2 more
core   +2 more sources